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Journal of Nuclear Medicine Technology

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Research ArticleImaging

Impact of Time-of-Flight PET/CT with a Large Axial Field of View for Reducing Whole-Body Acquisition Time

Go Akamatsu, Koji Uba, Takafumi Taniguchi, Katsuhiko Mitsumoto, Akihiro Narisue, Yuji Tsutsui and Masayuki Sasaki
Journal of Nuclear Medicine Technology June 2014, 42 (2) 101-104; DOI: https://doi.org/10.2967/jnmt.114.140665
Go Akamatsu
1Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
2Division of Molecular Imaging, Institute of Biomedical Research and Innovation, Kobe Japan
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Koji Uba
3Department of Radiological Technology, Saga University Hospital, Saga, Japan
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Takafumi Taniguchi
1Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
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Katsuhiko Mitsumoto
1Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
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Akihiro Narisue
3Department of Radiological Technology, Saga University Hospital, Saga, Japan
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Yuji Tsutsui
4Department of Medical Technology, Kyushu University Hospital, Fukuoka, Japan
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Masayuki Sasaki
1Department of Health Sciences, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
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  • FIGURE 1.
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    FIGURE 1.

    A 3D emission acquisition of 39- (upper) and 52-ring (lower) scanners. The 52-ring scanner has large acceptance angle. Thus, system sensitivity of 52-ring scanner is higher than that of 39-ring scanner.

  • FIGURE 2.
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    FIGURE 2.

    PET images reconstructed using OSEM + PSF + TOF with various acquisition times, different activity levels, and 2 types of detector ring. In terms of background uniformity, images acquired using 52-ring scanner were superior to those acquired using 39-ring scanner.

  • FIGURE 3.
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    FIGURE 3.

    CV for OSEM + PSF + TOF images in relation to acquisition times. CV of 52-ring scanner was superior to that of 39-ring scanner by approximately 10%. CV of 52-ring scanner using 3-min acquisition was equivalent to that of 39-ring scanner using 4-min acquisition.

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    FIGURE 4.

    Relative RC curves at 10-min acquisition in relation to reconstruction methods and number of detector rings. Although PSF and TOF also increased RC, RC curves were nearly identical independent of number of detector rings.

Tables

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    TABLE 1

    Sensitivities of 39- and 52-Ring PET/CT Scanners

    ParameterD (cm)39-ring system52-ring system
    Sensitivity (kcps/MBq)05.49.2
    105.99.4
    Total sensitivity (kcps/MBq)5.69.3
    • D = radial distance in from center of FOV.

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    TABLE 2

    NECR in Relation to Activity Level and Number of Detectors

    ParameterNECR (kcps)
    52-ring high activity115.9
    52-ring low activity59.0
    39-ring high activity72.0
    39-ring low activity37.8
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Journal of Nuclear Medicine Technology: 42 (2)
Journal of Nuclear Medicine Technology
Vol. 42, Issue 2
June 1, 2014
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Impact of Time-of-Flight PET/CT with a Large Axial Field of View for Reducing Whole-Body Acquisition Time
Go Akamatsu, Koji Uba, Takafumi Taniguchi, Katsuhiko Mitsumoto, Akihiro Narisue, Yuji Tsutsui, Masayuki Sasaki
Journal of Nuclear Medicine Technology Jun 2014, 42 (2) 101-104; DOI: 10.2967/jnmt.114.140665

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Impact of Time-of-Flight PET/CT with a Large Axial Field of View for Reducing Whole-Body Acquisition Time
Go Akamatsu, Koji Uba, Takafumi Taniguchi, Katsuhiko Mitsumoto, Akihiro Narisue, Yuji Tsutsui, Masayuki Sasaki
Journal of Nuclear Medicine Technology Jun 2014, 42 (2) 101-104; DOI: 10.2967/jnmt.114.140665
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Keywords

  • axial field of view
  • time-of-flight
  • PET/CT
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  • sensitivity
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