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Review ArticleTEACHING CASE STUDIES

The Role of Scintigraphy in Confirmation of Suspected Brain Death

Prashant Jolepalem and Helena R. Balon
Journal of Nuclear Medicine Technology December 2013, 41 (4) 306-307; DOI: https://doi.org/10.2967/jnmt.113.127639
Prashant Jolepalem
Department of Diagnostic Radiology and Molecular Imaging, Oakland University William Beaumont School of Medicine and Beaumont Health System, Royal Oak, Michigan
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Helena R. Balon
Department of Diagnostic Radiology and Molecular Imaging, Oakland University William Beaumont School of Medicine and Beaumont Health System, Royal Oak, Michigan
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Figures

  • FIGURE 1.
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    FIGURE 1.

    Non–contrast-enhanced CT scan showing diffuse cerebral edema, bilateral sulcal effacement, and loss of gray matter–white matter differentiation. Occipital lobe is spared.

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    FIGURE 2.

    (A) Regional cerebral blood flow MR perfusion study showing diffusely decreased perfusion to basal ganglia and thalami and mild reduction in cerebral cortex. (B) Cerebral perfusion study with normal findings is shown for comparison. (Courtesy of Department of MR Physics, Lund University, Lund, Sweden.)

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    FIGURE 3.

    Follow-up CT scan showing progressive diffuse cerebral edema and interval development of basal cistern effacement. These findings were compatible with impending transtentorial herniation.

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    FIGURE 4.

    SPECT images after 99mTc-HMPAO administration displayed as volume-rendered maximum-intensity projection (MIP) and tomographic slices in 3 planes. Images demonstrate activity in scalp, lacrimal glands, and salivary glands but absence of cerebral perfusion.

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Journal of Nuclear Medicine Technology: 41 (4)
Journal of Nuclear Medicine Technology
Vol. 41, Issue 4
December 1, 2013
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The Role of Scintigraphy in Confirmation of Suspected Brain Death
Prashant Jolepalem, Helena R. Balon
Journal of Nuclear Medicine Technology Dec 2013, 41 (4) 306-307; DOI: 10.2967/jnmt.113.127639

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The Role of Scintigraphy in Confirmation of Suspected Brain Death
Prashant Jolepalem, Helena R. Balon
Journal of Nuclear Medicine Technology Dec 2013, 41 (4) 306-307; DOI: 10.2967/jnmt.113.127639
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Keywords

  • Neurology
  • pediatrics
  • SPECT
  • brain death
  • cerebral perfusion scintigraphy
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