Article Figures & Data
Figures
- FIGURE 1.
Comparison of good injections via intraperitoneal (A) and intravenous (B) methods on small-animal PET maximum-intensity-projection images of body and tail, with proximal and distal limits of ROI indicated in yellow. For intraperitoneal method, mean-voxel is 2.6 %ID/g and maximum-voxel is 9.6 %ID/g. For intravenous method, mean-voxel is 2.9 %ID/g and maximum-voxel is 9.9 %ID/g.
- FIGURE 2.
Comparison of intermediate (A) and poor (B) injections via intravenous method on small-animal PET maximum-intensity-projection images of body and tail, with proximal and distal limits of ROI indicated in yellow. For intermediate injection, mean-voxel is 11.4 %ID/g and maximum-voxel is 60 %ID/g. For poor injection, mean-voxel is 28.4 %ID/g and maximum-voxel is 169 %ID/g.
- FIGURE 3.
Comparison of false-negative good (A) and false-positive intermediate (B) intravenous injections on small-animal PET maximum-intensity-projection images of body and tail, with proximal and distal limits of ROI indicated in yellow. For false-negative good injection, mean-voxel is 6.0 %ID/g and maximum-voxel is 33.6 %ID/g. For false-positive intermediate injection, mean-voxel is 3.6 %ID/g and maximum-voxel is 19.8 %ID/g.
- FIGURE 4.
Correlation of image-derived mean-voxel radioactivity and ex vivo (well counter) radioactivity fitted with linear regression. Dotted line is line of identity. r = 0.98. r2 = 0.95.
Tables
Parameter Average mean-voxel Average maximum-voxel Mean ± SD 3.0 ± 0.7 11.8 ± 1.7 Range 2.2–4.4 9.6–13.5 Data are %ID/g.
Quantitative Low Medium High Qualitative n Avg Max n Avg Max n Avg Max Sum Good 42 2.4 ± 0.7 9.0 ± 3.5 1 6.0 33.6 0 43 Intermediate 4 3.5 ± 0.3 21.4 ± 2.4 2 8.4 ± 4.2 45 ± 20.6 0 6 Poor 0 0 1 28.4 169 1 Sum 46 3 1 50 Avg = average mean-voxel; Max = average maximum-voxel.
Data are %ID/g with or without SD.
Parameter Negative Positive Total True 42 3 45/50 False 1 4 5/50 Negative = successful injection; positive = interstitial injection.
