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Research ArticleIMAGING

Assessment of Patient Exposure to X-Radiation from SPECT/CT Scanners

Narihiro Hara, Masahisa Onoguchi, Kenichi Takenaka, Kousuke Matsubara, Hiroyuki Ujita and Youichi Kenko
Journal of Nuclear Medicine Technology September 2010, 38 (3) 138-148; DOI: https://doi.org/10.2967/jnmt.110.075770
Narihiro Hara
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Masahisa Onoguchi
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Kenichi Takenaka
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Kousuke Matsubara
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Hiroyuki Ujita
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Youichi Kenko
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  • FIGURE 1.
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    FIGURE 1.

    (A) Pencil-shaped ionization chamber dosimeter. (B) PMMA cylindric head phantom. (C) PMMA cylindric abdominal phantom. (D) Layout of measurement system setup.

  • FIGURE 2.
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    FIGURE 2.

    Alderson RANDO anthropomorphic phantom for deep-body total absorbed dose measurement.

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    FIGURE 3.

    CTDIvol measurement results of PMMA cylindric head phantom (A) and cylindric abdominal phantom (B) at each tube voltage and current. Actual V = actual measured values; Index V = index values.

  • FIGURE 4.
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    FIGURE 4.

    TLD measurement results of each organ in anthropomorphic phantom: head region, brain (A); head region, eyes (B); cervical region, thyroid glands (C); thoracic region, lungs (D). Bra = Brain; Thy = Thyroid glands.

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    FIGURE 5.

    TLD measurement results of each organ in anthropomorphic phantom: thoracic region, mediastinum (A); thoracic region, skin (B); abdominal region, liver (C); abdominal region, kidneys (D). Medi = mediastinum; Kid = kidneys; Live = Liver; Sk1 = skin of thoracic region.

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    FIGURE 6.

    TLD measurement results of each organ in anthropomorphic phantom: pelvic region, urinary bladder (A); pelvic region, muscles (B); pelvic region, skin (C). Blad = urinary bladder; mus = muscles; Sk2 = skin of pelvic region.

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    FIGURE 7.

    TLD measurement results of each organ in anthropomorphic phantom: abdominal region, small intestine (A); abdominal region, large intestine (B); abdominal region, bones (C); pelvic region, ovaries (D). Bon = bones; La_int = large intestine; Sm_int = small intestine; Ova = ovaries.

Tables

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    TABLE 1

    Calculated TLD-to-CTDIvol Ratios for Head Region

    90 kVp120 kVp140 kVp
    mAsTDLCTDIvolRatioTDLCTDIvolRatioTDLCTDIvolRatio
    Brain
     251.391.800.773.213.800.855.085.500.92
     502.763.500.797.297.600.9610.1810.900.93
     1004.987.100.7012.6115.200.8320.5121.900.94
     1507.8210.600.7419.6022.800.8627.3732.800.83
     20011.2014.100.7925.0530.400.8238.8443.700.89
     25013.9317.100.8132.4838.100.8549.9854.700.91
     30017.0021.200.8037.7947.700.7965.0765.600.99
    Eyes
     251.941.801.083.713.800.985.445.500.99
     503.443.500.988.827.601.1613.6610.901.25
     1006.567.100.9215.2215.201.0023.7321.901.08
     1509.2710.600.8721.1122.800.9330.1432.800.92
     20014.9214.101.0628.8130.400.9546.7943.701.07
     25018.9317.101.1134.6138.100.9156.3054.701.03
     30020.3121.200.9649.7247.701.0469.7665.601.06
    • Data are milligrays.

    • View popup
    TABLE 2

    Calculated TLD-to-CTDIvol Ratios for Cervical and Thoracic Regions

    90 kVp120 kVp140 kVp
    mAsTDLCTDIvolRatioTDLCTDIvolRatioTDLCTDIvolRatio
    Thyroid
     252.210.802.774.871.802.716.802.702.52
     504.701.503.1311.343.503.2415.185.502.76
     1008.623.002.8723.277.003.3231.8211.002.89
     15012.974.602.8230.1810.602.8538.7016.502.35
     20019.496.103.2042.0314.102.9862.4422.002.84
     25024.767.603.2646.1717.602.6266.1227.502.40
     30025.889.102.8459.8321.102.8481.2132.902.47
    Lung
     251.510.801.893.761.802.095.452.702.02
     503.101.502.077.413.502.1211.035.502.00
     1006.253.002.0814.667.002.0922.2111.002.02
     1508.994.601.9622.6710.602.1432.6416.501.98
     20012.426.102.0428.7214.102.0443.4922.001.98
     25015.117.601.9936.6017.602.0852.8327.501.92
     30018.429.102.0242.6521.102.0265.6132.901.99
    Mediastinum
     251.540.801.933.871.802.155.902.702.19
     503.261.502.177.913.502.2611.275.502.05
     1006.293.002.1015.377.002.2023.1611.002.11
     1509.394.602.0423.9510.602.2634.3616.502.08
     20012.516.102.0529.9214.102.1245.2722.002.06
     25015.807.602.0839.2017.602.2355.7927.502.03
     30019.349.102.1345.0521.102.1370.6432.902.15
    Thoracic skin
     251.280.801.603.371.801.874.292.701.59
     502.711.501.817.243.502.079.945.501.81
     1005.213.001.7414.197.002.0320.5211.001.87
     1508.214.601.7820.0410.601.8928.9116.501.75
     20012.156.101.9927.2114.101.9342.6422.001.94
     25014.767.601.9431.6217.601.8045.6027.501.66
     30016.159.101.7841.5921.101.9749.8432.901.52
    • Data are milligrays.

    • View popup
    TABLE 3

    Calculated TLD-to-CTDIvol Ratios for Abdominal and Pelvic Regions

    90 kVp120 kVp140 kVp
    mAsTDLCTDIvolRatioTDLCTDIvolRatioTDLCTDIvolRatio
    Liver
     251.400.801.763.641.802.025.372.701.99
     502.991.501.997.413.502.1210.695.501.94
     1006.163.002.0513.887.001.9821.0111.001.91
     1509.294.602.0222.1310.602.0930.8216.501.87
     20011.196.101.8329.8114.102.1142.0422.001.91
     25014.807.601.9532.6417.601.8550.0827.501.82
     30018.239.102.0043.2321.102.0562.1932.901.89
    Kidney1.360.801.693.311.801.845.032.701.86
     252.811.501.885.553.501.599.465.501.72
     505.293.001.7613.457.001.9220.0811.001.83
     1008.594.601.8717.4610.601.6529.8616.501.81
     1509.996.101.6425.2114.101.7939.0722.001.78
     20014.187.601.8728.4217.601.6147.7127.501.73
     25016.059.101.7637.8121.101.7958.6432.901.78
     3001.360.801.693.311.801.845.032.701.86
    Small intestine
     251.140.801.432.921.801.624.162.701.54
     502.461.501.645.603.501.609.155.501.66
     1004.783.001.5911.847.001.6916.4911.001.50
     1507.294.601.5817.6510.601.6725.0816.501.52
     2009.696.101.5922.7214.101.6134.5822.001.57
     25012.187.601.6028.8217.601.6444.2327.501.61
     30013.819.101.5234.9421.101.6650.7532.901.54
    Large intestine
     251.060.801.322.641.801.473.852.701.43
     502.211.501.475.503.501.578.935.501.62
     1004.503.001.5011.157.001.5916.0211.001.46
     1506.334.601.3815.2710.601.4424.4116.501.48
     2009.086.101.4922.8114.101.6232.3622.001.47
     25011.217.601.4827.2717.601.5540.5227.501.47
     30013.299.101.4631.5921.101.5045.0232.901.37
    Ovary
     250.900.801.132.301.801.283.592.701.33
     501.791.501.194.823.501.387.375.501.34
     1003.723.001.249.097.001.3014.5211.001.32
     1505.384.601.1714.4410.601.3620.5716.501.25
     2008.206.101.3419.0114.101.3531.5422.001.43
     2509.067.601.1923.8017.601.3535.2327.501.28
     30011.229.101.2329.9921.101.4241.9032.901.27
    Urinary bladder
     251.070.801.342.561.801.424.112.701.52
     502.131.501.425.523.501.588.175.501.49
     1004.353.001.4510.477.001.5016.2111.001.47
     1506.014.601.3116.6810.601.5722.6616.501.37
     2007.616.101.2520.3414.101.4433.1422.001.51
     25010.297.601.3525.4117.601.4438.6427.501.41
     30013.099.101.4430.5521.101.4544.2332.901.34
    Red bone marrow
     251.110.801.382.921.801.624.332.701.60
     502.291.501.535.553.501.598.725.501.58
     1004.653.001.5510.837.001.5517.8811.001.63
     1506.844.601.4916.8310.601.5924.5516.501.49
     2008.596.101.4123.3214.101.6536.5622.001.66
     25011.027.601.4526.9917.601.5342.1427.501.53
     30013.249.101.4533.5021.101.5952.0732.901.58
    Muscle
     251.280.801.603.191.801.774.292.701.59
     502.681.501.796.393.501.839.645.501.75
     1005.603.001.8711.937.001.7020.3511.001.85
     1508.174.601.7818.9410.601.7929.4116.501.78
     20010.906.101.7925.1514.101.7838.0422.001.73
     25013.117.601.7231.0917.601.7745.1427.501.64
     30016.939.101.8640.7821.101.9354.4032.901.65
    Pelvic skin
     251.230.801.532.691.801.494.002.701.48
     502.341.501.565.523.501.588.565.501.56
     1004.733.001.5810.217.001.4615.2411.001.39
     1507.554.601.6415.3410.601.4521.4116.501.30
     2007.876.101.2920.2914.101.4429.4922.001.34
     25012.147.601.6024.9317.601.4238.5827.501.40
     30013.899.101.5330.8421.101.4644.1032.901.34
    • Data are milligrays.

    • View popup
    TABLE 4

    MIRD and TLD Values of Total Radiation Exposure in Brain and Liver

    Head regionAbdominal region
    Imaging conditionBrain perfusion scintigraphy (N-isopropyl-4-iodoamphetamine(123I) hydrochloride, 111 MBq)CT (brain)Total radiation exposure (mGy)Liver scintigraphy (galactosyl human serum albumin diethylenetriamine pentaacetic acid, 185 MBq)CT (liver)Total radiation exposure (mGy)
    90 kVp
     25 mAs2.52+1.393.919.99+1.4011.39
     50 mAs+2.765.28+2.9912.98
     100 mAs+4.987.50+6.1616.15
     150 mAs+7.8210.34+9.2919.28
     200 mAs+11.2013.72+11.1921.18
     250 mAs+13.9316.45+14.8024.79
     300 mAs+17.0019.52+18.2328.22
    120 kVp
     25 mAs2.52+3.215.739.99+3.6413.63
     50 mAs+7.299.81+7.4117.40
     100 mAs+12.6115.13+13.8823.87
     150 mAs+19.6022.12+22.1332.12
     200 mAs+25.0527.57+29.8139.80
     250 mAs+32.4835.00+32.6442.63
     300 mAs+37.7940.31+43.2353.22
    140 kVp
     25 mAs2.52+5.087.609.99+5.3720.68
     50 mAs+10.1812.70+10.6920.68
     100 mAs+20.5123.03+21.0131.00
     150 mAs+27.3729.89+30.8240.81
     200 mAs+38.8341.35+42.0452.03
     250 mAs+49.9852.50+50.0860.07
     300 mAs+65.0767.59+62.1972.18
    • View popup
    APPENDIX 1

    Exposure Doses in Head Region According to MIRD Method

    Organ111In-diethylenetriaminepentaacetic acidN-isopropyl-4-iodoamphetamine(123I) hydrochloride123I-iomazenil99mTc-ethyl cysteinate dimer
    Brain410.840.440.0051
    Body1.50.380.170.001
    • Organ-absorbed doses are given in mGy/37 MBq, except for 99mTc-ethyl cysteinate dimer, which is given in mGy/Bq.

    • View popup
    APPENDIX 2

    Exposure Doses in Cervical Region According to MIRD Method

    Organ123I capsule131I capsule99mTcO4−
    Thyroid131,3000.11
    Body0.0290.710.09
    • Organ-absorbed doses are given in mGy/37 MBq.

    • View popup
    APPENDIX 3

    Exposure Doses in Thoracic Region According to MIRD Method

    Organ99mTc-human serum albumin diethylenetriamine pentaacetic acid99mTc-tetrofosmin (rest)99mTc-methoxyisobutylisonitrile (rest)201TlCl123I-15-(4-iodophenyl)-3(R,S)-methylpentadecanoic acid99mTc-macroaggregated albumin81mKr gas
    Heart0.640.00410.346.40.057——
    Lung0.170.00230.0452.4—317
    Liver0.570.00320.144.70.0380.430.27
    Kidney0.480.01040.624.00.0111.10.1
    Body0.160.00380.0891.70.010.190.04
    • Organ-absorbed doses are given in mGy/37 MBq for 99mTc-human serum albumin diethylenetriamine pentaacetic acid, 99mTc-methoxyisobutylisonitrile, 201TlCl, and 99mTc-macroaggregated albumin; mGy/MBq for 99mTc-tetrofosmin and 123I-15-(4-iodophenyl)-3(R,S)-methylpentadecanoic acid; and μGy/37 MBq for 81mKr gas.

    • View popup
    APPENDIX 4

    Exposure Doses in Abdominal Region According to MIRD Method

    Organ99mTc-stannous colloid99mTc-N-pyridoxyl-5-methyltryptophan99mTc-galactosyl human serum albumin diethylenetriamine pentaacetic acid99mTc-mercaptoacetylglycylglycylglycin131I-adosterol
    Liver3.20.50.0540.00068.0
    Kidney—0.20.00810.00284.6
    Ovaries0.060.9——40.3
    Body0.20.20.00110.0014.4
    • Organ-absorbed doses are given in mGy/37 MBq for 99mTc-stannous colloid and 99mTc-N-pyridoxyl-5-methyltryptophan, mGy/MBq for 99mTc-galactosyl human serum albumin diethylenetriamine pentaacetic acid and 99mTc-mercaptoacetylglycylglycylglycin, and mGy/18.5 MBq for 131I-adosterol.

    • View popup
    APPENDIX 5

    Exposure Doses in Total Body According to MIRD Method

    Organ99mTc-hydroxymethylenediphosphonate99mTc-methylenediphosphonate67Ga-citrate201TlCl18F-FDG
    Liver0.0860.074.64.73.7
    Kidney0.2190.814.144.4
    Ovaries0.10.092.87.11.9
    Bone0.5120.464.4——
    Bone marrow (red)0.331———1.7
    Body0.1190.072.61.71.9
    • Organ-absorbed doses are given in mGy/37 MBq.

    • View popup
    APPENDIX 6

    Philips Dose-Management List

    FeatureDescription
    1: IntelliBeam filtration
    2-1: DoseRight automatic current selection
    2-2: DoseRight dose modulationAuto current selection (ACS)
    Dynamic dose modulation (D-DOM)
    Z-direction dose modulation (Z-DOM)
    3-1: DoseRight cardiac
    3-2: DoseRight electrocardiogram-gated modulationCardiac dose modulation
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Journal of Nuclear Medicine Technology: 38 (3)
Journal of Nuclear Medicine Technology
Vol. 38, Issue 3
September 1, 2010
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Assessment of Patient Exposure to X-Radiation from SPECT/CT Scanners
Narihiro Hara, Masahisa Onoguchi, Kenichi Takenaka, Kousuke Matsubara, Hiroyuki Ujita, Youichi Kenko
Journal of Nuclear Medicine Technology Sep 2010, 38 (3) 138-148; DOI: 10.2967/jnmt.110.075770

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Assessment of Patient Exposure to X-Radiation from SPECT/CT Scanners
Narihiro Hara, Masahisa Onoguchi, Kenichi Takenaka, Kousuke Matsubara, Hiroyuki Ujita, Youichi Kenko
Journal of Nuclear Medicine Technology Sep 2010, 38 (3) 138-148; DOI: 10.2967/jnmt.110.075770
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