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A Postprocessing Method for Compensation of Scatter and Collimator Blurring in SPECT: A Proof-of-Concept Study

Yan Yan and Gengsheng Lawrence Zeng
Journal of Nuclear Medicine Technology June 2009, 37 (2) 83-90; DOI: https://doi.org/10.2967/jnmt.108.061135

Article Figures & Data

Figures

  • FIGURE 1. 
    FIGURE 1. 

    Computer simulations. (A) Uniform object used for 2D PSF estimations. Eight point sources with different locations are marked by plus signs. (B) Cold-lesion simulation. This object consists of 5 cylindric cold spots in uniformly attenuating cylinder of uniform activity. (C) Uniform cardiac simulation.

  • FIGURE 2. 
    FIGURE 2. 

    Variations of gaussian parameters for 8 point sources as function of radial distance d: relative volume A (A), FWHM in tangential direction of fitted gaussian function (B), and FWHM in radial direction of fitted gaussian function (C).

  • FIGURE 3. 
    FIGURE 3. 

    (A) Spatially variant 2D PSF along radial direction of uniform water filled cylinder; (B) further blurred image using rotational convolution; and (C) profile comparison of 2D PSF before and after rotational convolution.

  • FIGURE 4. 
    FIGURE 4. 

    Comparison of 2D PSF calculated from Monte Carlo simulations, reconstruction approach, and fitted gaussian: radial direction (A); tangential direction (B). Profiles are plotted on logarithmic scales.

  • FIGURE 5. 
    FIGURE 5. 

    (A) Cold-lesion simulation with locations of region of interest used for contrast analysis, (B) raw reconstructed image with attenuation compensation but without scatter correction, (C) restored image with scatter compensation using our proposed method, and (D) vertical profiles through center of images.

  • FIGURE 6. 
    FIGURE 6. 

    (A) Uniform cardiac simulation with location of region of interest used for contrast analysis, (B) raw reconstructed image with attenuation compensation but without scatter correction, (C) restored image with scatter compensation using our proposed method, and (D) vertical profiles through center of images.

  • FIGURE 7. 
    FIGURE 7. 

    (A) Jaszczak phantom, (B) raw reconstructed image, and (C) restored image using proposed method.

  • FIGURE 1A. 
    FIGURE 1A. 

    Profile of raw images along major axis in logarithmic scale.

Tables

  • TABLE 1

    Comparisons of Image Quality for Computer Simulation Results

    SimulationTrue imageRaw imageRestored image
    Cold lesion
     SSE06.963.51
     Contrast 110.640.75
     Contrast 210.720.78
     Contrast 310.820.84
     Contrast 410.870.89
     Noise00.0660.027
    Uniform cardiac
     SSE08.334.48
     Contrast0.660.470.56
     Noise00.0380.045
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