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Journal of Nuclear Medicine Technology

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OtherCONTINUING EDUCATION

Nuclear Medicine and Infection Detection: The Relative Effectiveness of Imaging with 111In-Oxine-, 99mTc-HMPAO-, and 99mTc-Stannous Fluoride Colloid-Labeled Leukocytes and with 67Ga-Citrate

Davina K. Hughes
Journal of Nuclear Medicine Technology December 2003, 31 (4) 196-201;
Davina K. Hughes
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  • FIGURE 1.
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    FIGURE 1.

    Imaging of IBD (pancolitis) with 99mTc-stannous fluoride colloid-labeled leukocytes. Image 1 h after injection (A), in conjunction with image 3 h after injection (B), shows clear segmental involvement.

  • FIGURE 2.
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    FIGURE 2.

    Imaging of Crohn’s disease with 99mTc-stannous fluoride colloid-labeled leukocytes. Image 1 h after injection (A), in conjunction with image 3 h after injection (B), shows moderate to intense localization in large and small intestine.

  • FIGURE 3.
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    FIGURE 3.

    Anterior acquisition of sequential blood-flow images in 99mTc-MDP study is important in diagnosis of osteomyelitis. Vascular activity is increased in left proximal tibia and knee.

  • FIGURE 4.
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    FIGURE 4.

    (A and B) 99mTc-MDP blood-pool images of region of interest are important in diagnosis of osteomyelitis. (C) Delayed imaging of 99mTc-MDP studies can give more detailed localization information concerning bone involved in infectious process. In addition to 99mTc-MDP imaging, radiolabeled leukocytes can be used in diagnostic procedure when investigating osteomyelitis. (D) For this patient, 99mTc-stannous fluoride colloid was administered 3 d after 99mTc-MDP. 99mTc-stannous fluoride colloid was imaged 3 h after injection.

  • FIGURE 5.
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    FIGURE 5.

    99mTc-MDP blood-pool phase (A) and delayed image (B) show abnormal uptake of tracer. (C) 67Ga-Citrate is used to ensure that increased bone activity is due to infection of bone—in this case, osteomyelitis.

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Journal of Nuclear Medicine Technology: 31 (4)
Journal of Nuclear Medicine Technology
Vol. 31, Issue 4
December 1, 2003
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Nuclear Medicine and Infection Detection: The Relative Effectiveness of Imaging with 111In-Oxine-, 99mTc-HMPAO-, and 99mTc-Stannous Fluoride Colloid-Labeled Leukocytes and with 67Ga-Citrate
Davina K. Hughes
Journal of Nuclear Medicine Technology Dec 2003, 31 (4) 196-201;

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Nuclear Medicine and Infection Detection: The Relative Effectiveness of Imaging with 111In-Oxine-, 99mTc-HMPAO-, and 99mTc-Stannous Fluoride Colloid-Labeled Leukocytes and with 67Ga-Citrate
Davina K. Hughes
Journal of Nuclear Medicine Technology Dec 2003, 31 (4) 196-201;
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    • Abstract
    • INFECTION RADIOPHARMACEUTICALS
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