Abstract
The radiochemical purity and stability of four commercial 99mTc-stannous diethylenetriaminepentaacetic acid (99mTc-Sn-DTPA) kits were evaluated. A chromatographic technique involving Gelman instant thin layer chromatography was utilized to distinguish between 99mTc-Sn-DTPA, 99mTc-pertechnetate (99mTcO4 –), and hydrolyzed reduced 99mTc (99mTc-HR). The radiochemical purity of the kits was consistently greater than 99.0% on the two consecutive days evaluated. The stability of the commercial kits was greater than 99.0% at 4 hr after preparation. However, breakdown of two commercial kits was observed 6 hr after radiopharmaceutical preparation. These kits had radiochemical purities of 85.7 and 86.6% at 6 hr after preparation.
Footnotes
↵* Present address: Section of Nuclear Medicine, Department of Medical Radiology, University of Illinois Medical Center, Chicago, Ill. 60612