PT  - JOURNAL ARTICLE
AU  - Cooper, Patricia A.
AU  - Zimmer, A. Michael
TI  - Radiochemical Purity and Stability of Commercial <sup>99m</sup>Tc-Stannous DTPA Kits Using a New Chromatography Technique
DP  - 1975 Dec 01
TA  - Journal of Nuclear Medicine Technology
PG  - 208--209
VI  - 3
IP  - 4
4099  - http://tech.snmjournals.org/content/3/4/208.short
4100  - http://tech.snmjournals.org/content/3/4/208.full
SO  - J. Nucl. Med. Technol.1975 Dec 01; 3
AB  - The radiochemical purity and stability of four commercial 99mTc-stannous diethylenetriaminepentaacetic acid (99mTc-Sn-DTPA) kits were evaluated. A chromatographic technique involving Gelman instant thin layer chromatography was utilized to distinguish between 99mTc-Sn-DTPA, 99mTc-pertechnetate (99mTcO4 –), and hydrolyzed reduced 99mTc (99mTc-HR). The radiochemical purity of the kits was consistently greater than 99.0% on the two consecutive days evaluated. The stability of the commercial kits was greater than 99.0% at 4 hr after preparation. However, breakdown of two commercial kits was observed 6 hr after radiopharmaceutical preparation. These kits had radiochemical purities of 85.7 and 86.6% at 6 hr after preparation.