RT Journal Article SR Electronic T1 Radiochemical Purity and Stability of Commercial 99mTc-Stannous DTPA Kits Using a New Chromatography Technique JF Journal of Nuclear Medicine Technology JO J. Nucl. Med. Technol. FD Society of Nuclear Medicine SP 208 OP 209 VO 3 IS 4 A1 Cooper, Patricia A. A1 Zimmer, A. Michael YR 1975 UL http://tech.snmjournals.org/content/3/4/208.abstract AB The radiochemical purity and stability of four commercial 99mTc-stannous diethylenetriaminepentaacetic acid (99mTc-Sn-DTPA) kits were evaluated. A chromatographic technique involving Gelman instant thin layer chromatography was utilized to distinguish between 99mTc-Sn-DTPA, 99mTc-pertechnetate (99mTcO4 –), and hydrolyzed reduced 99mTc (99mTc-HR). The radiochemical purity of the kits was consistently greater than 99.0% on the two consecutive days evaluated. The stability of the commercial kits was greater than 99.0% at 4 hr after preparation. However, breakdown of two commercial kits was observed 6 hr after radiopharmaceutical preparation. These kits had radiochemical purities of 85.7 and 86.6% at 6 hr after preparation.