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Journal of Nuclear Medicine Technology

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OtherIMAGING

99mTc-DMSA Absolute Uptake: Normal Pediatric Values at 2–4 Hours

Rachael Moorin
Journal of Nuclear Medicine Technology March 2001, 29 (1) 22-29;
Rachael Moorin
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  • FIGURE 1.
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    FIGURE 1.

    Box-plots of absolute uptake of DMSA by sex. The box represents Quartile 1, Median and Quartile 3 of the data points. Whiskers show min to max data points, out to 1.5 X Interquartile range. The mean is indicated by a point within the box.

  • FIGURE 2.
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    FIGURE 2.

    Scatter-plot of age of child against DMSA absolute uptake.

  • FIGURE 3.
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    FIGURE 3.

    Scatter-plot of DMSA injected (mg) against DMSA absolute uptake.

  • FIGURE 4.
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    FIGURE 4.

    Residual plots for multiple regression analysis. The fit of the regression line is examined by plotting the differences between the observed and predicted values of y, the residuals. Outliers are points with unusually large residuals. The residuals above the regression line should ideally mirror those below.

  • FIGURE 5.
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    FIGURE 5.

    Residual plots excluding the 4 outliers.

  • FIGURE 6.
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    FIGURE 6.

    Plot of 95% confidence intervals for age of child against DMSA absolute uptake. Confidence intervals are used to estimate the mean of the future observations of the population.

  • FIGURE 7.
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    FIGURE 7.

    Plot of 95% confidence intervals for DMSA injected against DMSA absolute uptake.

  • FIGURE 8.
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    FIGURE 8.

    Plot of 95% prediction intervals for age of child against DMSA absolute uptake. Prediction intervals are used to estimate a single future observation within the population.

  • FIGURE 9.
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    FIGURE 9.

    Plot of 95% prediction intervals for DMSA injected against DMSA absolute uptake.

  • FIGURE 10.
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    FIGURE 10.

    Plot of DMSA absolute uptake against time between injection and scanning.

  • FIGURE 11.
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    FIGURE 11.

    Plot of age against DMSA injected (mg).

  • FIGURE 12.
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    FIGURE 12.

    Plot of example prediction intervals for age and DMSA uptake with a standard injection of 0.36mg DMSA (calculated using the regression equation).

Tables

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    Table 1

    Mean and standard deviation of DMSA absolute uptake (mg) for girls and boys

    GroupMean DMSA uptake (mg)Standard DeviationNumber of kidneys
    Female0.015610.0080356
    Male0.016390.0102332
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    Table 2

    Correlation of paired variables

    Variables PlottedCorrelation (Pearson’s)P-valueCorrelation grade
    DMSA uptake v Age0.770<0.0005HIGH
    DMSA uptake v Time0.2230.036POOR
    DMSA uptake v DMSA inj.0.940<0.0005HIGH
    Age v Time0.2380.025POOR
    Age v DMSA inj.0.671<0.0005GOOD
    Time v DMSA inj0.1580.140POOR
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    Table 3

    Correlation of paired variables with case number 6R and 6L excluded

    Variables Plotted Excluding case 6R&LCorrelation (Pearson’s)P-valueCorrelation grade
    DMSA uptake v Age0.802<0.0005HIGH
    DMSA uptake v Time0.2170.045POOR
    DMSA uptake v DMSA inj.0.943<0.0005HIGH
    Age v Time0.2350.029POOR
    Age v DMSA inj.0.737<0.0005GOOD
    Time v DMSA inj0.1480.174POOR
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Journal of Nuclear Medicine Technology: 29 (1)
Journal of Nuclear Medicine Technology
Vol. 29, Issue 1
March 1, 2001
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99mTc-DMSA Absolute Uptake: Normal Pediatric Values at 2–4 Hours
Rachael Moorin
Journal of Nuclear Medicine Technology Mar 2001, 29 (1) 22-29;

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99mTc-DMSA Absolute Uptake: Normal Pediatric Values at 2–4 Hours
Rachael Moorin
Journal of Nuclear Medicine Technology Mar 2001, 29 (1) 22-29;
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