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Journal of Nuclear Medicine Technology

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Review ArticleTeaching Case Study

The Role of Scintigraphy in Confirmation of Suspected Brain Death

Prashant Jolepalem and Helena R. Balon
Journal of Nuclear Medicine Technology October 2013, jnmt.113.127639; DOI: https://doi.org/10.2967/jnmt.113.127639
Prashant Jolepalem
Department of Diagnostic Radiology and Molecular Imaging, Oakland University William Beaumont School of Medicine and Beaumont Health System, Royal Oak, Michigan
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Helena R. Balon
Department of Diagnostic Radiology and Molecular Imaging, Oakland University William Beaumont School of Medicine and Beaumont Health System, Royal Oak, Michigan
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Abstract

We present a case illustrating how cerebral perfusion scintigraphy can be used to assist in crucial medical decision making in the intensive care setting for patients who are maintained on life support but are clinically suspected to have brain death. Cerebral perfusion scintigraphy can confirm brain death but cannot be used to diagnose it. 99mTc-HMPAO and 99mTc-ethylcysteinate dimer are the preferred imaging agents since they cross the blood–brain barrier.

  • neurology
  • pediatrics
  • SPECT
  • brain death
  • cerebral perfusion scintigraphy

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Journal of Nuclear Medicine Technology: 53 (1)
Journal of Nuclear Medicine Technology
Vol. 53, Issue 1
March 1, 2025
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The Role of Scintigraphy in Confirmation of Suspected Brain Death
Prashant Jolepalem, Helena R. Balon
Journal of Nuclear Medicine Technology Oct 2013, jnmt.113.127639; DOI: 10.2967/jnmt.113.127639

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The Role of Scintigraphy in Confirmation of Suspected Brain Death
Prashant Jolepalem, Helena R. Balon
Journal of Nuclear Medicine Technology Oct 2013, jnmt.113.127639; DOI: 10.2967/jnmt.113.127639
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Keywords

  • Neurology
  • pediatrics
  • SPECT
  • brain death
  • cerebral perfusion scintigraphy
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