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Journal of Nuclear Medicine Technology

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Nuclear Pharmacy

A Safe, Simple Method for Preparing Heat-Damaged Red Cells for Diagnosing Splenic Infarct or Trauma

Graeme M. Snowdon
Journal of Nuclear Medicine Technology September 1998, 26 (3) 204-205;
Graeme M. Snowdon
Department of Nuclear Medicine, Royal North Shore Hospital, Sydney, Australia
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Abstract

Objective: The purpose of this study was to demonstrate a fast, safe and simple method for preparing heat-damaged red blood cells.

Methods: Patient blood was radiolabeled using the Ultra-Tag® RBC kit and then heated to 49.5°C for 20 min. The reaction vial was cooled in ice water for 1 min and the required activity was administered to the patient. The patient was imaged 60 min postinjection.

Results: High-quality planar and SPECT images of the spleen were obtained with low background activity noted. Radiolabeling efficiency was greater than 95%.

Conclusion: The method was safe and simple to perform. High-quality images of the spleen were obtained.

  • technetium-99m-RBC
  • UltraTag®
  • heat-damaged red cells
  • spleen imaging
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Journal of Nuclear Medicine Technology: 26 (3)
Journal of Nuclear Medicine Technology
Vol. 26, Issue 3
September 1, 1998
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A Safe, Simple Method for Preparing Heat-Damaged Red Cells for Diagnosing Splenic Infarct or Trauma
Graeme M. Snowdon
Journal of Nuclear Medicine Technology Sep 1998, 26 (3) 204-205;

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A Safe, Simple Method for Preparing Heat-Damaged Red Cells for Diagnosing Splenic Infarct or Trauma
Graeme M. Snowdon
Journal of Nuclear Medicine Technology Sep 1998, 26 (3) 204-205;
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More in this TOC Section

  • Evaluation of an Alternative Radiochemical Purity Testing Method for Technetium-99m-Sestamibi
  • Experimental Determination of Dose Calibrator Settings and Study of Associated Volume Dependence in V-Vials for Rhenium-186 Perrhenate Solution Sources
  • The Effect of Vincristine on the Biodistribution of Technetium-99m DTPA, GHA, and DMSA in Balb/c Female Mice
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Keywords

  • technetium-99m-RBC
  • UltraTag®
  • heat-damaged red cells
  • spleen imaging
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