PT  - JOURNAL ARTICLE
AU  - Graeme M. Snowdon
TI  - A Safe, Simple Method for Preparing Heat-Damaged Red Cells for Diagnosing Splenic Infarct or Trauma
DP  - 1998 Sep 01
TA  - Journal of Nuclear Medicine Technology
PG  - 204--205
VI  - 26
IP  - 3
4099  - http://tech.snmjournals.org/content/26/3/204.short
4100  - http://tech.snmjournals.org/content/26/3/204.full
SO  - J. Nucl. Med. Technol.1998 Sep 01; 26
AB  - Objective: The purpose of this study was to demonstrate a fast, safe and simple method for preparing heat-damaged red blood cells. Methods: Patient blood was radiolabeled using the Ultra-Tag® RBC kit and then heated to 49.5°C for 20 min. The reaction vial was cooled in ice water for 1 min and the required activity was administered to the patient. The patient was imaged 60 min postinjection. Results: High-quality planar and SPECT images of the spleen were obtained with low background activity noted. Radiolabeling efficiency was greater than 95%. Conclusion: The method was safe and simple to perform. High-quality images of the spleen were obtained.