Skip to main content

Main menu

  • Home
  • Content
    • Current
      • JNMT Supplement
    • Ahead of print
    • Past Issues
    • Continuing Education
    • JNMT Podcast
    • SNMMI Annual Meeting Abstracts
  • Subscriptions
    • Subscribers
    • Rates
    • Journal Claims
    • Institutional and Non-member
  • Authors
    • Submit to JNMT
    • Information for Authors
    • Assignment of Copyright
    • AQARA Requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
    • Corporate & Special Sales
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNMT
    • JNM
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine Technology
  • SNMMI
    • JNMT
    • JNM
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • My Cart
Journal of Nuclear Medicine Technology

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • Continuing Education
    • JNMT Podcast
    • SNMMI Annual Meeting Abstracts
  • Subscriptions
    • Subscribers
    • Rates
    • Journal Claims
    • Institutional and Non-member
  • Authors
    • Submit to JNMT
    • Information for Authors
    • Assignment of Copyright
    • AQARA Requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
    • Corporate & Special Sales
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • Watch or Listen to JNMT Podcast
  • Visit SNMMI on Facebook
  • Join SNMMI on LinkedIn
  • Follow SNMMI on Twitter
  • Subscribe to JNMT RSS feeds
Imaging

Measurement of Blood Radioactivity for Quantification of Cerebral Blood Flow Using a Gamma Camera

Kenya Murase, Hiroyoshi Fujioka, Takeshi Inoue, Yoshihiro Ishimaru, Akihisa Akamune, Yuji Yamamoto and Junpei Ikezoe
Journal of Nuclear Medicine Technology September 1998, 26 (3) 191-195;
Kenya Murase
Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun; and Departments of Radiology and Neurosurgery, Matsuyama Shimin Hospital, Ohte-machi, Matsuyama, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Hiroyoshi Fujioka
Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun; and Departments of Radiology and Neurosurgery, Matsuyama Shimin Hospital, Ohte-machi, Matsuyama, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Takeshi Inoue
Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun; and Departments of Radiology and Neurosurgery, Matsuyama Shimin Hospital, Ohte-machi, Matsuyama, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yoshihiro Ishimaru
Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun; and Departments of Radiology and Neurosurgery, Matsuyama Shimin Hospital, Ohte-machi, Matsuyama, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Akihisa Akamune
Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun; and Departments of Radiology and Neurosurgery, Matsuyama Shimin Hospital, Ohte-machi, Matsuyama, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yuji Yamamoto
Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun; and Departments of Radiology and Neurosurgery, Matsuyama Shimin Hospital, Ohte-machi, Matsuyama, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Junpei Ikezoe
Department of Radiology, Ehime University School of Medicine, Shitsukawa, Shigenobu-cho, Onsen-gun; and Departments of Radiology and Neurosurgery, Matsuyama Shimin Hospital, Ohte-machi, Matsuyama, Japan
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • PDF
Loading

Abstract

Objective: This study was designed to determine whether gamma cameras can be substituted for well-type scintillation counters in measuring blood radioactivity counts to be used as an input function for the quantitative measurement of cerebral blood flow (CBF).

Methods: Twelve different aqueous 123I solutions were prepared by serial dilution of the original concentration of 281.9 kBq/ml, and the radioactivity count of each dilution was measured with a gamma camera with the collimator removed, and with a well-type scintillation counter. When measuring the radioactivity counts with a gamma camera, static images were acquired using a 128 × 128 matrix for 5 min, and the regions of interest with 14 × 14 pixels (21 mm × 21 mm) were defined.

Results: There was a good correlation between the results obtained by these two procedures in the range of concentration between 0.008 kBq/ml and 281.9 kBq/ml (y = 4.245x – 2.549, r = 1.0, n = 12, s.e.e. = 7.217 kcpm). There was good agreement between the CBF values (ml/100 g/min) obtained using the cross-calibration factor (CCF) and blood radioactivity counts measured with the two procedures (y = 0.990x + 0.552, r = 0.990, n = 231, s.e.e. = 1.340 ml/100 g/min).

Conclusion: The results suggest that gamma cameras can be substituted for well-type scintillation counters in the quantitative measurement of CBF, and make it unnecessary to measure CCF after routine calibration of a SPECT apparatus.

  • gamma camera
  • well-type scintillation counter
  • blood radioactivity
  • cerebral blood flow
  • cross-calibration factor
PreviousNext
Back to top

In this issue

Journal of Nuclear Medicine Technology: 26 (3)
Journal of Nuclear Medicine Technology
Vol. 26, Issue 3
September 1, 1998
  • Table of Contents
  • Index by author
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine Technology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Measurement of Blood Radioactivity for Quantification of Cerebral Blood Flow Using a Gamma Camera
(Your Name) has sent you a message from Journal of Nuclear Medicine Technology
(Your Name) thought you would like to see the Journal of Nuclear Medicine Technology web site.
Citation Tools
Measurement of Blood Radioactivity for Quantification of Cerebral Blood Flow Using a Gamma Camera
Kenya Murase, Hiroyoshi Fujioka, Takeshi Inoue, Yoshihiro Ishimaru, Akihisa Akamune, Yuji Yamamoto, Junpei Ikezoe
Journal of Nuclear Medicine Technology Sep 1998, 26 (3) 191-195;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Measurement of Blood Radioactivity for Quantification of Cerebral Blood Flow Using a Gamma Camera
Kenya Murase, Hiroyoshi Fujioka, Takeshi Inoue, Yoshihiro Ishimaru, Akihisa Akamune, Yuji Yamamoto, Junpei Ikezoe
Journal of Nuclear Medicine Technology Sep 1998, 26 (3) 191-195;
Twitter logo Facebook logo LinkedIn logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Early 10-Minute Postinjection [18F]F-FAPI-42 uEXPLORER Total-Body PET/CT Scanning Protocol for Staging Lung Cancer Using HYPER Iterative Reconstruction
  • Single- Versus Dual-Time-Point Imaging for Transthyretin Cardiac Amyloid Using 99mTc-Pyrophosphate
  • Effectiveness of Data-Driven Gating FDG PET/CT for Abdominal Region
Show more Imaging

Similar Articles

Keywords

  • gamma camera
  • well-type scintillation counter
  • blood radioactivity
  • cerebral blood flow
  • cross-calibration factor
SNMMI

© 2025 SNMMI

Powered by HighWire