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Research ArticleImaging

The Effect of 131I Therapy on the Eradication of Helicobacter pylori in Patients with Thyroid Disorders: A Preliminary Study

Farhad Pourfarzi, Hossein Pakrouy, Ali Mohammadian Erdi and Elnaz Faghfuri
Journal of Nuclear Medicine Technology January 2024, jnmt.123.266508; DOI: https://doi.org/10.2967/jnmt.123.266508
Farhad Pourfarzi
1Digestive Disease Research Center, Ardabil University of Medical Sciences, Ardabil, Iran;
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Hossein Pakrouy
2Ardabil Nuclear Medicine Center, Ardabil University of Medical Sciences, Ardabil, Iran; and
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Ali Mohammadian Erdi
3Department of Anesthesiology, School of Medicine, Ardabil University of Medical Sciences, Ardabil, Iran
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Elnaz Faghfuri
1Digestive Disease Research Center, Ardabil University of Medical Sciences, Ardabil, Iran;
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    TABLE 1.

    Clinical and Therapeutic Details of 18 Patients with DTC or Hyperthyroidism and H. pylori Infection Treated with 131I

    Patient no.Age (y)SexDiagnosisTreatment dose (GBq)Hp stool Ag before 131IHp stool Ag after 131I
    158MHT0.74PositivePositive
    244FPTC0.15PositivePositive
    360FPTC0.2PositivePositive
    436FPTC0.2PositivePositive
    561MPTC5.5PositivePositive
    650FPTC5.5PositivePositive
    738FPTC5.5PositivePositive
    843FPTC3.7PositivePositive
    943MHT1.1PositivePositive
    1043FPTC5.5PositivePositive
    1131FPTC0.2PositivePositive
    1233FPTC5.5PositivePositive
    1350FPTC3.7PositivePositive
    1441FPTC5.5PositiveNegative
    • Hp = H. pylori; Ag = antigen; HT = hyperthyroidism; PTC = papillary thyroid carcinoma.

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    TABLE 2.

    Comparison of Present Findings with Previous Findings on 131I Effect on H. pylori Eradication

    Hp-positive patients before 131I therapy (n)131I therapy dose (GBq)Hp-negative patients after 131I therapy (n)Test used to evaluate Hp infectionReference
    14 with HT or PTC0.15–5.51SATPresent study
    71 with DTC3.7–7.423UBT(11)
    42 with DTCNA5UBT(14)
    18 with DTC3.7–7.40SAT(17)
    • Hp = H. pylori; HT = hyperthyroidism; PTC = papillary thyroid carcinoma; SAT = stool antigen test; UBT = urea breath test; NA = not applicable.

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Journal of Nuclear Medicine Technology: 53 (1)
Journal of Nuclear Medicine Technology
Vol. 53, Issue 1
March 1, 2025
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The Effect of 131I Therapy on the Eradication of Helicobacter pylori in Patients with Thyroid Disorders: A Preliminary Study
Farhad Pourfarzi, Hossein Pakrouy, Ali Mohammadian Erdi, Elnaz Faghfuri
Journal of Nuclear Medicine Technology Jan 2024, jnmt.123.266508; DOI: 10.2967/jnmt.123.266508

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The Effect of 131I Therapy on the Eradication of Helicobacter pylori in Patients with Thyroid Disorders: A Preliminary Study
Farhad Pourfarzi, Hossein Pakrouy, Ali Mohammadian Erdi, Elnaz Faghfuri
Journal of Nuclear Medicine Technology Jan 2024, jnmt.123.266508; DOI: 10.2967/jnmt.123.266508
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Keywords

  • Helicobacter pylori
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