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Case ReportTeaching Case Study

Concurrent Intrathyroidal Follicular Variant of Papillary Thyroid Carcinoma with Malignant Struma Ovarii Presenting 12 Years After Initial Diagnosis

Bhakti Vaidya and Sandip Basu
Journal of Nuclear Medicine Technology July 2023, jnmt.122.265385; DOI: https://doi.org/10.2967/jnmt.122.265385
Bhakti Vaidya
Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Hospital Annexe, and Homi Bhabha National Institute, Mumbai, India
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Sandip Basu
Radiation Medicine Centre, Bhabha Atomic Research Centre, Tata Memorial Hospital Annexe, and Homi Bhabha National Institute, Mumbai, India
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  • FIGURE 1.
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    FIGURE 1.

    (A–E) Posttherapy 131I scan (anterior images) demonstrating iodine uptake in pelvic lesion after first RAI cycle (A), second cycle (B), third cycle (C), fourth cycle (D), and fifth cycle (E), showing progressive response. (F and G) Posterior images demonstrating iodine uptake in lung nodules and pelvic lesions after first RAI cycle (F) and after fifth cycle (G).

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    FIGURE 2.

    Maximum-intensity projection image of 18F-FDG PET/CT scan showing very low-grade 18F-FDG uptake (arrows) in pelvic mass (A), right internal iliac deposit (B) and lung nodules (C). (A–C) Left-side images are fused PET/CT axial images, and right-side images are CT axial images.

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    TABLE 1.

    Thyroglobulin and Thyroid-Stimulating Hormone Values over Course of Treatment from Baseline to Last Follow-up

    TimeThyroglobulin (ng/mL)Thyroid- stimulating hormone (μIU/mL)
    Thyroid-stimulating hormone stimulated
     Baseline (before first RAI cycle)>3001.67
     6 mo after first RAI cycle>30013.98
     1 y after second RAI cycle30058
     1 y after third RAI cycle28852
     1 y after fourth RAI cycle/ before fifth RAI cycle26946.6
    Thyroid-stimulating hormone suppressed
     Recent follow-up (6 mo after fifth RAI cycle)750.008
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Journal of Nuclear Medicine Technology: 53 (1)
Journal of Nuclear Medicine Technology
Vol. 53, Issue 1
March 1, 2025
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Concurrent Intrathyroidal Follicular Variant of Papillary Thyroid Carcinoma with Malignant Struma Ovarii Presenting 12 Years After Initial Diagnosis
Bhakti Vaidya, Sandip Basu
Journal of Nuclear Medicine Technology Jul 2023, jnmt.122.265385; DOI: 10.2967/jnmt.122.265385
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Keywords

  • malignant struma ovarii
  • follicular variant of papillary thyroid carcinoma
  • quality of life
  • radioiodine therapy
  • 131I
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Concurrent Intrathyroidal Follicular Variant of Papillary Thyroid Carcinoma with Malignant Struma Ovarii Presenting 12 Years After Initial Diagnosis
Bhakti Vaidya, Sandip Basu
Journal of Nuclear Medicine Technology Jul 2023, jnmt.122.265385; DOI: 10.2967/jnmt.122.265385

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