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Research ArticleSpecial Contributions

Gastric Emptying Studies in Pediatrics: A Cincinnati Children’s Hospital Experience

Joseph (Joby) MacLean and Khalil El-Chammas
Journal of Nuclear Medicine Technology March 2024, 52 (1) 40-45; DOI: https://doi.org/10.2967/jnmt.123.266857
Joseph (Joby) MacLean
1Nuclear Medicine Section, Department of Radiology, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio; and
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Khalil El-Chammas
2Division of Gastroenterology, Hepatology, and Nutrition, Cincinnati Children’s Hospital Medical Center, Cincinnati, Ohio
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  • FIGURE 1.
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    FIGURE 1.

    Epic schedule template for gastric emptying studies. Central scheduling can schedule 3 gastric emptying studies in 1 d. Scheduling template is blocked as “permission” in afternoon to allow for gastric emptying studies to be performed over 4 h.

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    FIGURE 2.

    Flow diagram of gastric emptying studies starting with dual-phase gastric emptying. Changes based on what patient can be fed are permitted.

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    TABLE 1.

    Gastric Emptying Dose Chart

    ExaminationRadiopharmaceuticalTarget doseOther
    Dual-phase gastric emptyingSolid (99mTc-sulfur colloid)7.4 MBq (0.200 mCi)Liquid eggs
    Liquid (67Ga-citrate)3.0 MBq (0.080 mCi)Water or apple juice
    Solid gastric emptying99mTc-sulfur colloid7.4 MBq (0.200 mCi)Liquid eggs or Ensure Plus
    Liquid gastric emptying99mTc-sulfur colloid7.4 MBq (0.200 mCi)Patient formula or water
    Liquid gastric emptying gastroesophageal reflux99mTc-sulfur colloid9.3 MBq (0.250 mCi)<2 y
    11.1 MBq (0.300 mCi)2–4 y
    14.8 MBq (0.400 mCi)≥5 y
    • Radiopharmaceutical dose chart taken from Cincinnati Children’s Hospital Medical Center’s Department of Nuclear Medicine radiopharmaceutical target dose schedule. 99mTc-macroaggregated albumin can be substituted for 99mTc-sulfur colloid if 99mTc-sulfur colloid is not available. 99mTc-DTPA can be used for clear-liquid gastric emptying studies using water.

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    TABLE 2.

    Reference Values for Various Types of Gastric Emptying Studies

    Study typeReference value
    Dual phase with egg (4-h study) (delayed solid emptying at 2 or 4 h is considered abnormal; delayed clear emptying at 1 or 2 h is considered abnormal)Liquid: >40% at 1 h; >78% at 2 h
    Solid: >10% but <70% at 1 h; >40% at 2 h; >90% at 4 h
    Solid-only with egg (4-h study) (delayed solid emptying at 2 or 4 h is considered abnormal)>10% but <70% at 1 h; >40% at 2 h; >90% at 4 h
    Solid-only with Ensure Plus (4-h study)>10% but <70% at 1 h; >40% at 2 h; >90% at 4 h
    Solid-only with oatmeal (1-h study)>50% at 1 h
    Liquid-only with formula or milk (2-h study)>51% at 2 h
    Clear liquid–only with water (30-min study)Half-time < 25 min
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Journal of Nuclear Medicine Technology: 52 (1)
Journal of Nuclear Medicine Technology
Vol. 52, Issue 1
March 1, 2024
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Gastric Emptying Studies in Pediatrics: A Cincinnati Children’s Hospital Experience
Joseph (Joby) MacLean, Khalil El-Chammas
Journal of Nuclear Medicine Technology Mar 2024, 52 (1) 40-45; DOI: 10.2967/jnmt.123.266857

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Gastric Emptying Studies in Pediatrics: A Cincinnati Children’s Hospital Experience
Joseph (Joby) MacLean, Khalil El-Chammas
Journal of Nuclear Medicine Technology Mar 2024, 52 (1) 40-45; DOI: 10.2967/jnmt.123.266857
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Keywords

  • dual-phase gastric emptying
  • gastric emptying
  • pediatrics
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