Multicenter Study of Quantitative SPECT: Reproducibility of 99mTc Quantitation Using a Conjugated-Gradient Minimization Reconstruction Algorithm

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FIGURE 1.
Representative slice of cylindric phantom. Gray circle indicates placement of region of interest on phantom.

TABLE 2

Bone SPECT Image Acquisition and Reconstruction Conditions Used for Clinical Conditions at Participating Institutions

	Acquisition			Reconstruction
Institution	Mode	Number of projections	Duration of projection (s)	Updates	Gaussian filter (full width at half maximum; mm)
A	Continuous	90	12	48 (2 subsets)	5
B	Step and shoot	120	10	30 (1 subsets)	6
C	Continuous	90	12	48 (2 subsets)	10
D	Continuous	120	9	30 (1 subsets)	7
E	Step and shoot	72	20	48 (2 subsets)	5
F	Continuous	72	16	40 (1)	7

TABLE 3

Radioactivity Concentrations in SPECT Images Under 2 Conditions at Participating Institutions

	Radioactivity concentrations in SPECT images (kBq/mL)
Institution	Standardized conditions	Clinical conditions
A	99.65 ± 0.24	102.29 ± 0.55
B	99.32 ± 0.40	99.90 ± 0.25
C	101.33 ± 0.36	103.77 ± 0.51
D	102.96 ± 0.37	104.09 ± 0.24
E	108.35 ± 0.36	108.49 ± 0.11
F	95.71 ± 0.60	96.78 ± 0.64