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Research ArticlePractical Protocol Tips

Lymphoscintigraphy: Breast and Melanoma

Kathy S. Thomas and Jessica Williams
Journal of Nuclear Medicine Technology December 2020, 48 (4) 315-316; DOI: https://doi.org/10.2967/jnmt.120.259101
Kathy S. Thomas
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Jessica Williams
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    TABLE 1

    Radiopharmaceuticals (1,2)

    IdentityDoseAdministration route
    99mTc-sulfur colloid (filtered or nonfiltered)Mean, 15 MBq (0.5 mCi); range, 15–35 MBq (0.5–1.0 mCi)Subdermal or intradermal
    99mTc-tilmanocept18.5 MBq (0.5 mCi)Subdermal or intradermal
    • View popup
    TABLE 2

    Standard Acquisition Parameters for Dynamic, Static, and Planar Imaging (1,2)

    CategoryParameter
    Camera typeLarge–field-of-view multidetector
    Energy peak140 keV
    Energy window20%
    CollimatorLow-energy high-resolution
    Patient position
     BreastSupine
     MelanomaSupine or prone
    Camera position, dual-head
     Detector 1Anterior
     Detector 2Posterior
    Camera position, single-headAnterior
    Injection-to-scan time
     Sulfur colloidImmediate
     99mTc-tilmanocept15-min delay
    Acquisition typeDynamic or planar
    Views
     BreastImmediate anterior images for ∼15–30 min; delayed anterior, oblique, or lateral images, as appropriate, for 3 h
     MelanomaImmediate anterior or posterior images for ∼30–60 min; additional anterior, oblique, or lateral images, as appropriate, for 1 h
    Matrix128 × 128 or 256 × 256
    Acquisition time
     Dynamic: breast30 s/frame for 2–30 min
     Dynamic: melanoma30 s/frame for 30–60 min
     Planar5–10 min/view
     Additional views5–10 min/view
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Journal of Nuclear Medicine Technology: 48 (4)
Journal of Nuclear Medicine Technology
Vol. 48, Issue 4
December 1, 2020
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Lymphoscintigraphy: Breast and Melanoma
Kathy S. Thomas, Jessica Williams
Journal of Nuclear Medicine Technology Dec 2020, 48 (4) 315-316; DOI: 10.2967/jnmt.120.259101
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    • CLINICAL INDICATIONS
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Lymphoscintigraphy: Breast and Melanoma
Kathy S. Thomas, Jessica Williams
Journal of Nuclear Medicine Technology Dec 2020, 48 (4) 315-316; DOI: 10.2967/jnmt.120.259101

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