Research ArticleImaging

Imaging of the Thyroid and Parathyroid Using a Cardiac Cadmium-Zinc-Telluride Camera: Phantom Studies

Yosuke Miyazaki, Yasuhiro Kato, Akira Imoto and Kazuki Fukuchi
Journal of Nuclear Medicine Technology March 2018, 46 (1) 39-44; DOI: https://doi.org/10.2967/jnmt.117.199042

Article Figures & Data

Figures

  • FIGURE 1.
    FIGURE 1.

    Typical thyroid images using 99mTc (top) and 123I (bottom) tracers. Shown are MIP images (left), PE images (middle), and NaI planar images (right).

  • FIGURE 2.
    FIGURE 2.

    Relationship between image counts and radioactivity of 99mTc-containing thyroid phantoms: NaI planar image (A), MIP image (B), and PE image (C).

  • FIGURE 3.
    FIGURE 3.

    Relationship between image counts and radioactivity of 123I thyroid phantoms: NaI planar image (A), MIP image (B), and PE image (C).

  • FIGURE 4.
    FIGURE 4.

    Typical early (A) and delayed (B) images from dual-phase 99mTc-sestamibi protocol using MIP. Clear accumulation of tracer is visible in lower quadrant of left thyroid lobe in delayed image.

  • FIGURE 5.
    FIGURE 5.

    Typical single-tracer (A), dual-tracer (B), and subtracted (C) images from 99mTc-sestamibi/99mTc-pertechnetate protocol using MIP. After single-tracer image was subtracted from dual-tracer image, solitary parathyroid adenoma was clearly visible.

  • FIGURE 6.
    FIGURE 6.

    Representative 99mTc photopeak (A), 123I photopeak (B), and subtracted (C) parathyroid images from 99mTc-sestamibi/123I-iodine protocol using MIP. 99mTc tracer is seen in thyroid and parathyroid glands, and 123I is distributed in thyroid tissue. Parathyroid adenoma was then clearly visualized by subtracting 123I image from 99mTc image.

Tables

  • TABLE 1

    Tracer Dose of Each Phantom in 3 Parathyroid Imaging Protocols

    ProtocolThyroid (MBq)Parathyroid (MBq)Background (MBq/mL)
    Dual-phase 99mTc-sestamibi
     Early phase (99mTc)4.00.10.02
     Delayed phase (99mTc)0.50.070.014
    Dual-tracer 99mTc-sestamibi/99mTc-pertechnetate
     Single tracer (99mTc)4.0—0.02
     Dual tracer (99mTc)8.00.10.04
    Dual-tracer 99mTc-sestamibi/123I-iodine
     99mTc4.00.10.02
     123I0.74—0.006
  • TABLE 2

    Energy Windows Used with CZT and NaI Cameras

    Single-tracer acquisition
    WindowCZT (keV)NaI (keV)Dual-tracer acquisition (CZT [keV])
    99mTc140.5% ± 10%140.5% ± 15%140.5% ± 5%
    123I159% ± 10%159% ± 15%159% ± 5%
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