Article Figures & Data
Figures
- FIGURE 1.
(A) Device design includes gelatin capsule containing central core of paraffin-surrounded radiolabeled rice grain. (B) Final assembled device is small and easily swallowed.
- FIGURE 2.
Images of device obtained using 57Co sheet source behind subject. (A) Device is seen immediately after being swallowed. (B) At 1 h, when device is used alone it is difficult to be confident that it has entered small bowel. (C) At 4 h, motion of device within small bowel during image acquisition can be seen. (D) At 6 h, device is likely at ileocecal junction. (E) At 8 h, device is likely in ascending colon. (F) At 24 h, device has been excreted.
- FIGURE 3.
Dual-isotope acquisitions with digitally fused images (as well as diagram of normal anatomy to help identify device location) in patient with history of constipation. Use of dual-isotope acquisitions in conjunction with gastric emptying study allows location of device to be defined more clearly. Device (open arrows) can be seen 1 h after being swallowed (A), is still in stomach at 4 h (B), is visible in small bowel at 6 h (C), is in transverse colon at 24 h (D), and is in rectosigmoid region at 48 h (E). An image obtained at 72 h showed no activity. M = point source markers placed on patient to right of midline approximately at levels of nipple and umbilicus to ensure consistent patient positioning between images.
Tables
Subject no. Symptoms Transit time Gastric emptying result Volunteers 1 None 21 h 30 min 2 None 22 h 18 min 3 None 13 h 0 min 4 None 7 h 0 min Average 15 h 57 min* Patients 1 Constipation 43 h 33 min 2 Constipation Withdrew 3 Constipation 46 h 46 min 4 Constipation 21 h 39 min Normal 5 Diarrhea 21 h 39 min Normal 6 Constipation 67 h 43 min Normal 7 Constipation 46 h 21 min Normal 8 Constipation 26 h 2 min Accelerated 9 Constipation 9 h 50 min Delayed 10 Constipation Withdrew Normal Average 40 h 45 min†
