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Research ArticlePractice Management

Assessment of 99mTc-Succimer Residual Activity Using Inert Nonreactive Syringes

Wendy Galbraith, Xinlian Chen, Katie Talley and Vesper Grantham
Journal of Nuclear Medicine Technology March 2015, 43 (1) 61-63; DOI: https://doi.org/10.2967/jnmt.114.147983
Wendy Galbraith
1University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma
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Xinlian Chen
1University of Oklahoma College of Pharmacy, Oklahoma City, Oklahoma
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Katie Talley
2OU Medical Center Children’s Hospital, Oklahoma City, Oklahoma; and
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Vesper Grantham
3College of Allied Health Department of Medical Imaging and Radiation Sciences, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma
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    FIGURE 1.

    Inert nonreactive syringe.

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    TABLE 1

    Factors Affecting Adsorption

    Factors affecting adsorptionReference
    Factors contributing to syringe adsorption
     Silicone or lubricant1
     Elastomeric plunger tips2,3,4
     Barrel4,5
     Volume of radiopharmaceutical in syringe6
     Rinsing during administration3,4
     Brand and lot of syringe2,4,7,8
    Factors not contributing to syringe adsorption
     Time > 30 min2,7
     Volume of radiopharmaceutical in syringe1,2,6
     Dead space in syringe if rinsed2
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    TABLE 2

    Results

    DescriptionSyringe ASyringe B
    Lab setting
     No. of syringes1212
     Activity range37–185 MBq37–185 MBq
     Residual average20.9% (SD, ±5.6)0.73% (SD, ±0.18)
    Clinic administration
     Syringes in clinic5277
     Activity range37–240 MBq21–218 MBq
     Residual range8.32%–73.91%1.49%–17.44%
     Residual average30.6% (SD, ±12.5)6.38% (SD, ±2.95)
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Journal of Nuclear Medicine Technology: 43 (1)
Journal of Nuclear Medicine Technology
Vol. 43, Issue 1
March 1, 2015
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Assessment of 99mTc-Succimer Residual Activity Using Inert Nonreactive Syringes
Wendy Galbraith, Xinlian Chen, Katie Talley, Vesper Grantham
Journal of Nuclear Medicine Technology Mar 2015, 43 (1) 61-63; DOI: 10.2967/jnmt.114.147983

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Assessment of 99mTc-Succimer Residual Activity Using Inert Nonreactive Syringes
Wendy Galbraith, Xinlian Chen, Katie Talley, Vesper Grantham
Journal of Nuclear Medicine Technology Mar 2015, 43 (1) 61-63; DOI: 10.2967/jnmt.114.147983
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Keywords

  • 99mTc-dimercaptosuccinic acid
  • succimer
  • syringe residual
  • radiopharmaceutical
  • administered activity
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