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Research ArticleIMAGING

Thermal Control of Brown Adipose Tissue in 18F-FDG PET

Annah Skillen, Geoffrey M. Currie and Janelle M. Wheat
Journal of Nuclear Medicine Technology June 2012, 40 (2) 99-103; DOI: https://doi.org/10.2967/jnmt.111.098780
Annah Skillen
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Geoffrey M. Currie
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Janelle M. Wheat
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  • FIGURE 1.
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    FIGURE 1.

    Numbers of patients with BAT between warmed and not-warmed cohorts, highlighting impact of warming overall and on men and women, respectively.

  • FIGURE 2.
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    FIGURE 2.

    A 28-y-old man with desmoplastic small-round-cell tumor presented in October 2009 for initial 18F-FDG PET study (left) and subsequently in January 2010 (right). Both studies used approximately 270 MBq of 18F-FDG and were obtained after 60-min uptake phase. Initial image was obtained without warming techniques. Follow-up image was obtained with warming intervention. Apart from disease progression, presence and absence of significant BAT accumulation is noted.

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    TABLE 1

    Summary of Respective Patient Demographics for the 2 Cohorts

    DemographicGroup A (not warmed)Group B (warmed)P
    Male88 (58.7%)95 (63.3%)0.407
    Female62 (41.3%)55 (36.7%)0.407
    Mean age (y)57.7 (95% CI, 54.8–60.6)61.0 (95% CI, 58.1–63.9)0.117
    Mean weight (kg)80.5 (95% CI, 77.3–83.6)78.2 (95% CI, 75.1–81.4)0.325
    Mean height (cm)171.7 (95% CI, 170.0–173.5)172.9 (95% CI, 171.1–174.6)0.381
    Mean BMI27.1 (95% CI, 26.2–28.0)26.0 (95% CI, 25.1–26.9)0.098
    Daily maximum temperature (°C)22.3 (95% CI, 21.7–22.9)29.2 (95% CI, 28.6–29.7)<0.0001
    Daily minimum temperature (°C)9.5 (95% CI, 8.9–10.0)19.0 (95% CI, 18.5–19.6)<0.0001
    • View popup
    TABLE 2

    Summary of BAT Statistics

    ParameterBAT presentNo BAT presentP
    Overall9.3% (95% CI, 6.5%–13.2%)90.7% (95% CI, 86.8%–93.5%)—
    Male10.9%89.1%0.310
    Female6.8%93.2%
    Mean age (y)45.4 (95% CI, 38.9–51.9)60.8 (95% CI, 58.7–62.9)<0.001
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Journal of Nuclear Medicine Technology: 40 (2)
Journal of Nuclear Medicine Technology
Vol. 40, Issue 2
June 1, 2012
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Thermal Control of Brown Adipose Tissue in 18F-FDG PET
Annah Skillen, Geoffrey M. Currie, Janelle M. Wheat
Journal of Nuclear Medicine Technology Jun 2012, 40 (2) 99-103; DOI: 10.2967/jnmt.111.098780
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Thermal Control of Brown Adipose Tissue in 18F-FDG PET
Annah Skillen, Geoffrey M. Currie, Janelle M. Wheat
Journal of Nuclear Medicine Technology Jun 2012, 40 (2) 99-103; DOI: 10.2967/jnmt.111.098780

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