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The Effect of Renal Failure on 18F-FDG Uptake: A Theoretic Assessment

Eric Laffon, Anne-Laure Cazeau, Antoine Monet, Henri de Clermont, Philippe Fernandez, Roger Marthan and Dominique Ducassou
Journal of Nuclear Medicine Technology December 2008, 36 (4) 200-202; DOI: https://doi.org/10.2967/jnmt.107.049627
Eric Laffon
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Anne-Laure Cazeau
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Antoine Monet
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Henri de Clermont
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Philippe Fernandez
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Roger Marthan
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Dominique Ducassou
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  • FIGURE 1. 
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    FIGURE 1. 

    Theoretic 18F-FDG blood time–activity curve for T1/2 = 37 min (patient with normal renal function) (1) and T1/2 = 110 min (limiting case) (2). Value of λCp(t = 0) has been arbitrarily set to 1. a.u. = arbitrary unit.

  • FIGURE 2. 
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    FIGURE 2. 

    Theoretic 18F-FDG tissue time–activity curve from Equation 4 for T1/2 = 37 min (1) and from Equation 5 for T1/2 = 110 min (2). Values of λCp(t = 0) and K have been arbitrarily set to 1 and 0.05 min−1, respectively. a.u. = arbitrary unit.

  • FIGURE 3. 
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    FIGURE 3. 

    Ratio R vs. time delay between 18F-FDG injection and PET acquisition for T1/2 = 37 min (patient with normal renal function) (1) and T1/2 = 110 min (limiting case) (2).

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Journal of Nuclear Medicine Technology: 36 (4)
Journal of Nuclear Medicine Technology
Vol. 36, Issue 4
December 2008
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The Effect of Renal Failure on 18F-FDG Uptake: A Theoretic Assessment
Eric Laffon, Anne-Laure Cazeau, Antoine Monet, Henri de Clermont, Philippe Fernandez, Roger Marthan, Dominique Ducassou
Journal of Nuclear Medicine Technology Dec 2008, 36 (4) 200-202; DOI: 10.2967/jnmt.107.049627

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The Effect of Renal Failure on 18F-FDG Uptake: A Theoretic Assessment
Eric Laffon, Anne-Laure Cazeau, Antoine Monet, Henri de Clermont, Philippe Fernandez, Roger Marthan, Dominique Ducassou
Journal of Nuclear Medicine Technology Dec 2008, 36 (4) 200-202; DOI: 10.2967/jnmt.107.049627
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