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Journal of Nuclear Medicine Technology

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OtherRADIOPHARMACY

Rapid Determination of the Radiochemical Purity of 99mTc-Antimony Trisulfide Colloid Prepared by Standard and Alternative Heating Methods

Douglas R. Smyth
Journal of Nuclear Medicine Technology September 2006, 34 (3) 174-178;
Douglas R. Smyth
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  • FIGURE 1. 
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    FIGURE 1. 

    RCPs, determined by SAX (○) and ITLC (♦) quality control methods, of 99mTc-ATC samples (n = 3) prepared with dry block heater set at 115°C for various durations.

  • FIGURE 2. 
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    FIGURE 2. 

    RCPs, determined by SAX (○) and ITLC (♦) quality control methods, of 99mTc-ATC samples (n = 3) prepared with dry block heater set at various temperatures for set time of 35 min.

  • FIGURE 3. 
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    FIGURE 3. 

    Plot of RCPs determined by SAX method vs. RCPs determined by ITLC method for each 99mTc-ATC sample tested in this study.

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    TABLE 1

    RCPs of 99mTc-ATC Determined by ITLC and SAX Methods (n = 3)

    RCP (%)
    30 min35 min
    MethodITLCSAX|Δ|ITLCSAX|Δ|
    Water bath at 100°C97.6 ± 0.998.0 ± 0.80.4 ± 0.198.1 ± 0.598.2 ± 0.50.1 ± 0.0
    Dry block at 21-mm and 100°C96.9 ± 0.497.3 ± 0.40.4 ± 0.097.6 ± 0.397.9 ± 0.30.3 ± 0.0
    Dry block at 21-mm and 115°C99.1 ± 0.299.3 ± 0.10.2 ± 0.199.3 ± 0.499.3 ± 0.30.2 ± 0.1
    Dry block at 26-mm and 115°C98.0 ± 0.498.3 ± 0.40.4 ± 0.198.5 ± 0.698.4 ± 0.20.4 ± 0.1
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Journal of Nuclear Medicine Technology: 34 (3)
Journal of Nuclear Medicine Technology
Vol. 34, Issue 3
September 2006
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Rapid Determination of the Radiochemical Purity of 99mTc-Antimony Trisulfide Colloid Prepared by Standard and Alternative Heating Methods
Douglas R. Smyth
Journal of Nuclear Medicine Technology Sep 2006, 34 (3) 174-178;

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Rapid Determination of the Radiochemical Purity of 99mTc-Antimony Trisulfide Colloid Prepared by Standard and Alternative Heating Methods
Douglas R. Smyth
Journal of Nuclear Medicine Technology Sep 2006, 34 (3) 174-178;
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