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Journal of Nuclear Medicine Technology

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OtherPharmacy

Intercomparison of Activity Measurements for β-Emitters in Swiss Nuclear Medicine Laboratories

Claude Wastiel, Jean-François Valley, Angelika Bischof Delaloye, Michel Leresche, Reto Linder, Manfred Sassowsky and François O. Bochud
Journal of Nuclear Medicine Technology December 2005, 33 (4) 238-242;
Claude Wastiel
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Jean-François Valley
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Angelika Bischof Delaloye
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Michel Leresche
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Reto Linder
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Manfred Sassowsky
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François O. Bochud
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  • FIGURE 1.
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    FIGURE 1.

    Intercomparison results for 90Y. First letter in laboratory code represents instrument brand (V, Veenstra; I, Isomed; A, Atomlab). Laboratory codes without decimal points represent laboratories with only 1 instrument. Laboratory codes with decimal points represent laboratories with different instruments. Dotted lines represent an arbitrary tolerance of ±20%. Ameas/Aref [−] = ratio of measured activity to reference activity.

  • FIGURE 2.
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    FIGURE 2.

    Intercomparison results for 169Er. Laboratory codes are as described in legend to Figure 1. Original measurement = measurements performed by laboratories according to their routine method. Correct bkg = measurements repeated by us with corrected background subtraction. Ameas/Aref [−] = ratio of measured activity to reference activity. *Measurements were performed with 32P scale.

  • FIGURE 3.
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    FIGURE 3.

    Ratio of activities measured in syringes and vials. Laboratory codes are as described in legend to Figure 1. Correct bkg = measurements repeated with special care concerning background subtraction. Ameas(syringe)/Aref(vial) [−] = ratio of measured activities in syringes to reference activities in vials. *Measurements were performed with 32P scale.

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    TABLE 1

    Measuring Methods Obtained from 22 Questionnaires

    RadionuclideNo. of laboratoriesNo. of laboratories performing measurements with:
    Original vialSyringeBothNothing (no measurements)
    90Y208453
    89Sr52012
    169Er133334
    153Sa121452
    186Re156333
    32P85120
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    TABLE 2

    Results Distributed According to Radionuclide and Type of Geometry

    ParameterValue for following radionuclide and geometry:
    90Y169Er
    Vial geometrySyringe geometryVial geometrySyringe* geometry
    Mean Ameas/Aref1.191.181.670.92
    SD0.190.244.870.53
    No. of measurements outside ±20% limit16/2714/2017/2211/14
    • ↵* Subsequent measurements and measurements performed with 32P scale were not considered.

    • Ameas/Aref = ratio of measured activities to reference activities.

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Journal of Nuclear Medicine Technology: 33 (4)
Journal of Nuclear Medicine Technology
Vol. 33, Issue 4
December 1, 2005
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Intercomparison of Activity Measurements for β-Emitters in Swiss Nuclear Medicine Laboratories
Claude Wastiel, Jean-François Valley, Angelika Bischof Delaloye, Michel Leresche, Reto Linder, Manfred Sassowsky, François O. Bochud
Journal of Nuclear Medicine Technology Dec 2005, 33 (4) 238-242;

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Intercomparison of Activity Measurements for β-Emitters in Swiss Nuclear Medicine Laboratories
Claude Wastiel, Jean-François Valley, Angelika Bischof Delaloye, Michel Leresche, Reto Linder, Manfred Sassowsky, François O. Bochud
Journal of Nuclear Medicine Technology Dec 2005, 33 (4) 238-242;
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