Skip to main content

Main menu

  • Home
  • Content
    • Current
      • JNMT Supplement
    • Ahead of print
    • Past Issues
    • Continuing Education
    • JNMT Podcast
    • SNMMI Annual Meeting Abstracts
  • Subscriptions
    • Subscribers
    • Rates
    • Journal Claims
    • Institutional and Non-member
  • Authors
    • Submit to JNMT
    • Information for Authors
    • Assignment of Copyright
    • AQARA Requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
    • Corporate & Special Sales
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • SNMMI
    • JNMT
    • JNM
    • SNMMI Journals
    • SNMMI

User menu

  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Nuclear Medicine Technology
  • SNMMI
    • JNMT
    • JNM
    • SNMMI Journals
    • SNMMI
  • Subscribe
  • My alerts
  • Log in
  • My Cart
Journal of Nuclear Medicine Technology

Advanced Search

  • Home
  • Content
    • Current
    • Ahead of print
    • Past Issues
    • Continuing Education
    • JNMT Podcast
    • SNMMI Annual Meeting Abstracts
  • Subscriptions
    • Subscribers
    • Rates
    • Journal Claims
    • Institutional and Non-member
  • Authors
    • Submit to JNMT
    • Information for Authors
    • Assignment of Copyright
    • AQARA Requirements
  • Info
    • Reviewers
    • Permissions
    • Advertisers
    • Corporate & Special Sales
  • About
    • About Us
    • Editorial Board
    • Contact Information
  • More
    • Alerts
    • Feedback
    • Help
    • SNMMI Journals
  • Watch or Listen to JNMT Podcast
  • Visit SNMMI on Facebook
  • Join SNMMI on LinkedIn
  • Follow SNMMI on Twitter
  • Subscribe to JNMT RSS feeds
Nuclear Pharmacy

Ultratag® RBC Kit for Combined Cardiac First-Pass and Multigated Acquisition Studies

Laurie E. Stallings, Kenneth T. Cheng, Kenneth M. Spicer, Ray Wiegner and James K. Humphries
Journal of Nuclear Medicine Technology March 1997, 25 (1) 44-48;
Laurie E. Stallings
Department of Nuclear Medicine, Medical University of South Carolina, Charleston, South Carolina
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kenneth T. Cheng
Department of Nuclear Medicine, Medical University of South Carolina, Charleston, South Carolina
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Kenneth M. Spicer
Department of Nuclear Medicine, Medical University of South Carolina, Charleston, South Carolina
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ray Wiegner
Department of Nuclear Medicine, Medical University of South Carolina, Charleston, South Carolina
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
James K. Humphries
Department of Nuclear Medicine, Medical University of South Carolina, Charleston, South Carolina
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • PDF
Loading

Abstract

The authors developed a procedure to use the in vitro Ultratag® (Mallinckrodt, St. Louis, MO) red blood cell (RBC) labeling kit for both first-pass (FP) and multigated acquisition (MUGA) studies with a high specific activity in a reduced volume (50 mCi/0.5 ml) and a high labeling efficiency that can be used with a single-crystal camera to yield a quality study.

Methods: A packed red blood cell (PRBC) bolus was created by two methods: (a) reducing the volume of the components of the Ultratag® kit and (b) centrifuging the final dose volume. The labeling efficiency of each bolus was evaluated, each PRBC bolus was visually inspected for clots and percent hemolysis was assessed using a hemocytometer at 30 min, 1 hr and 2 hr postcentrifugation.

Results: Use of the first method, the 50% kit, provided the best results. However, the resulting volume from this kit only approached 1 ml, which is not clinically adequate for a first-pass study. In the second method, the total volume was centrifuged to form a PRBC bolus, which appeared to be stable in the syringe for at least 2 hr. 3A combined FP/MUGA study from a centrifuged 50% reduced kit was performed in one normal subject as a preliminary assessment of the clinical utility of this procedure. The image quality of the scan is diagnostically adequate.

Conclusion: By using the in vitro Ultratag® kit, a compact PRBC bolus was created that was stable in the syringe and could be reinjected safely into the patient for combined cardiac FP/MUGA studies.

  • first-pass studies
  • multigated acquisition
  • technetium-99m-red blood cell labeling
PreviousNext
Back to top

In this issue

Journal of Nuclear Medicine Technology: 25 (1)
Journal of Nuclear Medicine Technology
Vol. 25, Issue 1
March 1, 1997
  • Table of Contents
  • Index by author
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on Journal of Nuclear Medicine Technology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Ultratag® RBC Kit for Combined Cardiac First-Pass and Multigated Acquisition Studies
(Your Name) has sent you a message from Journal of Nuclear Medicine Technology
(Your Name) thought you would like to see the Journal of Nuclear Medicine Technology web site.
Citation Tools
Ultratag® RBC Kit for Combined Cardiac First-Pass and Multigated Acquisition Studies
Laurie E. Stallings, Kenneth T. Cheng, Kenneth M. Spicer, Ray Wiegner, James K. Humphries
Journal of Nuclear Medicine Technology Mar 1997, 25 (1) 44-48;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Ultratag® RBC Kit for Combined Cardiac First-Pass and Multigated Acquisition Studies
Laurie E. Stallings, Kenneth T. Cheng, Kenneth M. Spicer, Ray Wiegner, James K. Humphries
Journal of Nuclear Medicine Technology Mar 1997, 25 (1) 44-48;
Twitter logo Facebook logo LinkedIn logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Bookmark this article

Jump to section

  • Article
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Evaluation of an Alternative Radiochemical Purity Testing Method for Technetium-99m-Sestamibi
  • Experimental Determination of Dose Calibrator Settings and Study of Associated Volume Dependence in V-Vials for Rhenium-186 Perrhenate Solution Sources
  • The Effect of Vincristine on the Biodistribution of Technetium-99m DTPA, GHA, and DMSA in Balb/c Female Mice
Show more Nuclear Pharmacy

Similar Articles

Keywords

  • first-pass studies
  • multigated acquisition
  • technetium-99m-red blood cell labeling
SNMMI

© 2025 SNMMI

Powered by HighWire