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Journal of Nuclear Medicine Technology

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Radiopharmacy

Determination of Radionuclide Impurities in Tc-99m: A Rapid Pulse Height Analysis Technique

Robert E. Ackerhalt and James A. Sondel
Journal of Nuclear Medicine Technology June 1979, 7 (2) 84-87;
Robert E. Ackerhalt
State University of New York at Buffalo, Buffalo, New York
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James A. Sondel
State University of New York at Buffalo, Buffalo, New York
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Abstract

We have developed a simple and rapid procedure for determining levels of multiple radionuclide impurities in Tc-99m generator eluates before use in patients. The technique combines the use of a low gamma energy filter comprised of layers of lead, cadmium, and copper to reduce the radiation from Tc-99m—with pulse height analysis of the transmitted high energy photons from common impurities such as Ru-103, I-131, and Mo-99. The procedure, which employs a multichannel analyzer and subsequent calculations, can be performed in almost the same time required for the current technique using isotope calibrators.

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Journal of Nuclear Medicine Technology: 7 (2)
Journal of Nuclear Medicine Technology
Vol. 7, Issue 2
June 1, 1979
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Determination of Radionuclide Impurities in Tc-99m: A Rapid Pulse Height Analysis Technique
Robert E. Ackerhalt, James A. Sondel
Journal of Nuclear Medicine Technology Jun 1979, 7 (2) 84-87;

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Determination of Radionuclide Impurities in Tc-99m: A Rapid Pulse Height Analysis Technique
Robert E. Ackerhalt, James A. Sondel
Journal of Nuclear Medicine Technology Jun 1979, 7 (2) 84-87;
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