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Journal of Nuclear Medicine Technology

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Amino Acid PET Imaging with 18F-DOPA in the evaluation of Pediatric Brain Tumors

Mehdi Djekidel, Rahaf Alsadi, Othmane Bouhali and Ata Ur Rehman Maaz
Journal of Nuclear Medicine Technology April 2022, jnmt.121.263050; DOI: https://doi.org/10.2967/jnmt.121.263050
Mehdi Djekidel
1 Department of Diagnostic Imaging, Division of Nuclear Medicine and Molecular Imaging, Sidra Medicine, Qatar;
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Rahaf Alsadi
2 Department of Science, Texas A&M University at Qatar;
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Othmane Bouhali
3 Science Department, Texas A&M University at Qatar;
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Ata Ur Rehman Maaz
4 Department of Pediatrics, Division of Hematology Oncology, Sidra Medicine, Qatar
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Abstract

Although MRI is the workhorse of brain tumor initial evaluation and follow-up, there is a growing amount of data recommending the incorporation of amino-acid PET imaging at different stages of the management of these patients. Recent nuclear medicine and neuro-oncology clinical practice recommendations support the use of amino-acid imaging in brain tumor imaging. Considering 18F-DOPA is FDA approved for the evaluation of parkinsonian syndromes, it could be used clinically for other valuable clinical indications such as brain tumor evaluations. This value seems to be well established in adults and has growing evidence for its use in pediatrics as well. We offer to present four pediatric brain tumor cases imaged with 18F-DOPA and review the literature.

  • Correlative Imaging
  • Molecular Imaging
  • MRI
  • Oncology: Brain
  • Pediatrics
  • PET/CT
  • PET/MRI
  • Radiation Therapy Planning
  • PET
  • amino acid imaging
  • brain tumors
  • nuclear medicine
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Journal of Nuclear Medicine Technology: 53 (1)
Journal of Nuclear Medicine Technology
Vol. 53, Issue 1
March 1, 2025
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Amino Acid PET Imaging with 18F-DOPA in the evaluation of Pediatric Brain Tumors
Mehdi Djekidel, Rahaf Alsadi, Othmane Bouhali, Ata Ur Rehman Maaz
Journal of Nuclear Medicine Technology Apr 2022, jnmt.121.263050; DOI: 10.2967/jnmt.121.263050

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Amino Acid PET Imaging with 18F-DOPA in the evaluation of Pediatric Brain Tumors
Mehdi Djekidel, Rahaf Alsadi, Othmane Bouhali, Ata Ur Rehman Maaz
Journal of Nuclear Medicine Technology Apr 2022, jnmt.121.263050; DOI: 10.2967/jnmt.121.263050
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Keywords

  • correlative imaging
  • molecular imaging
  • MRI
  • Oncology: Brain
  • pediatrics
  • PET/CT
  • PET/MRI
  • radiation therapy planning
  • PET
  • amino acid imaging
  • brain tumors
  • nuclear medicine
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