Technical Aspects and Administration Methods of Lutetium177 Lu Dotatate for Nuclear Medicine Technologists

Abstract

At Banner MD Anderson Cancer Center in Arizona, we gained valuable knowledge of the different infusion methods for 177 Lu-DOT-AO-Tyr3-Octreotate (Lutetium Lu-177 dotatate, Lutathera, PRRT). Our nuclear medicine department utilized two different methods of administration called the gravity infusion method and the infusion pump protocol. The experience we had with these methods allowed us to identify aspects of the gravity infusion method that were problematic which lead us to search for and implement the infusion pump protocol. The pump protocol ensured that the infusion process of administering Lu-177 dotatate was a safe and consistent dose delivery for every patient.