Brain Imaging—PET: Amyloid

Article Figures & Data

TABLE 1.

Radiopharmaceutical Identity, Dose, and Route of Administration

Identity	Dose	Route of administration
¹⁸F-florbetapir (Amyvid; Lilly)	370 MBq (10 mCi)	Intravenous
¹⁸F-florbetaben (NeuraCeq; Life Molecular Imaging)	300 MBq (8 mCi)	Intravenous
¹⁸F-flutemetamol (Vizamyl; GE HealthCare)	185 MBq (5 mCi)	Intravenous

TABLE 2.

Acquisition Parameters: PET or PET/CT

Parameter	Specification	Standard/preferred/optional
Camera type	PET/CT	Preferred
	PET	Standard
Energy peak	511 keV	Standard
Injection to imaging time
¹⁸F-florbetapir	30–50 min after injection	Standard
¹⁸F-florbetaben	45–130 min after injection	Standard
¹⁸F-flutemetamol	60–120 min after injection	Standard
Attenuation correction	PET/CT: CT acquisition	Standard
	PET: cesium or germanium sources	Standard
Patient position	Supine	Standard
Arm position	Arms down	Standard
Acquisition mode	2- or 3-dimensional	Standard (camera-dependent)
Bed positions	1	Standard
Time per bed position
¹⁸F-florbetapir	10 min	Standard
¹⁸F-florbetaben	15–20 min	Standard
¹⁸F-flutemetamol	10–20 min	Standard
View	Head	Standard
CT acquisition	Per the manufacturer’s recommendations for attenuation correction or diagnostic imaging	Optional