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Research ArticlePractice Standards

SNMMI Procedure Standard/EANM Practice Guideline for Molecular Breast Imaging with Dedicated γ-Cameras

Carrie B. Hruska, Christinne Corion, Lioe-Fee de Geus-Oei, Beatriz E. Adrada, Amy M. Fowler, Katie N. Hunt, S. Cheenu Kappadath, Patrick Pilkington, Lenka M. Pereira Arias-Bouda and Gaiane M. Rauch
Journal of Nuclear Medicine Technology June 2022, 50 (2) 103-110; DOI: https://doi.org/10.2967/jnmt.121.264204
Carrie B. Hruska
1Department of Radiology, Mayo Clinic, Rochester, Minnesota;
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Christinne Corion
2Department of Surgery, Haaglanden Medical Center, The Hague, Netherlands;
3Department of Radiology, Leiden University Medical Center, Leiden, Netherlands;
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Lioe-Fee de Geus-Oei
3Department of Radiology, Leiden University Medical Center, Leiden, Netherlands;
4Biomedical Photonic Imaging Group, University of Twente, Enschede, Netherlands;
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Beatriz E. Adrada
5Department of Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas;
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Amy M. Fowler
6Department of Radiology, University of Wisconsin, Madison, Wisconsin;
7Department of Medical Physics, University of Wisconsin, Madison, Wisconsin;
8University of Wisconsin Carbone Cancer Center, Madison, Wisconsin;
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Katie N. Hunt
1Department of Radiology, Mayo Clinic, Rochester, Minnesota;
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S. Cheenu Kappadath
9Department of Medical Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas;
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Patrick Pilkington
10Department of Nuclear Medicine, University Hospital 12 de Octubre, Madrid, Spain;
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Lenka M. Pereira Arias-Bouda
3Department of Radiology, Leiden University Medical Center, Leiden, Netherlands;
11Department of Nuclear Medicine, Alrijne Hospital, Leiderdorp, Netherlands; and
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Gaiane M. Rauch
5Department of Breast Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas;
12Department of Abdominal Imaging, The University of Texas MD Anderson Cancer Center, Houston, Texas
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Tables

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    TABLE 1.

    Radiation Dosimetry Estimates in Adults

    RadiopharmaceuticalRadiation dose to the breast (mGy/MBq [rad/mCi])Organ receiving largest radiation dose (mGy/MBq [rad/mCi])Effective dose (mSv/MBq [rem/mCi])
    99mTc-sestamibi, resting subject0.0038 (0.014)Gallbladder: 0.039 (0.14)0.0071* to 0.0090 (0.026–0.033)
    99mTc-tetrofosmin, resting subject0.0020 (0.0074)Gallbladder: 0.036 (0.13)0.0062* to 0.0080 (0.023–0.030)
    • Unless otherwise noted, data are from ICRP Publication 128 (55).

    • * An updated estimate of effective dose specific to female subjects was provided in Andersson et al. (56).

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    TABLE 2.

    Fetal Dose from 99mTc-Sestamibi (Rest)

    Fetal dose
    Stage of gestationmGy/MBqrad/mCi
    Early0.0150.055
    3 mo0.0120.044
    6 mo0.00840.031
    9 mo0.00540.020
    • ↵99mTc-sestamibi dose estimates to fetus are from Russell et al. (57). No information about possible placental crossover of this compound was available for use in estimating fetal doses.

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Journal of Nuclear Medicine Technology: 50 (2)
Journal of Nuclear Medicine Technology
Vol. 50, Issue 2
June 1, 2022
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SNMMI Procedure Standard/EANM Practice Guideline for Molecular Breast Imaging with Dedicated γ-Cameras
Carrie B. Hruska, Christinne Corion, Lioe-Fee de Geus-Oei, Beatriz E. Adrada, Amy M. Fowler, Katie N. Hunt, S. Cheenu Kappadath, Patrick Pilkington, Lenka M. Pereira Arias-Bouda, Gaiane M. Rauch
Journal of Nuclear Medicine Technology Jun 2022, 50 (2) 103-110; DOI: 10.2967/jnmt.121.264204
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  • Article
    • PREAMBLE
    • I. INTRODUCTION
    • II. GOALS
    • III. COMMON CLINICAL INDICATIONS
    • IV. CONTRAINDICATIONS
    • V. QUALIFICATIONS AND RESPONSIBILITIES OF PERSONNEL
    • VI. PROCEDURE/SPECIFICATIONS OF THE EXAMINATION
    • VII. DOCUMENTATION/REPORTING
    • VIII. EQUIPMENT SPECIFICATIONS
    • IX. QUALITY CONTROL
    • X. PATIENT EDUCATION
    • XI. RADIATION SAFETY
    • XII. APPROVAL
    • XIII. LIABILITY STATEMENT
    • XIV. ACKNOWLEDGMENTS
    • XV. REFERENCES
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SNMMI Procedure Standard/EANM Practice Guideline for Molecular Breast Imaging with Dedicated γ-Cameras
Carrie B. Hruska, Christinne Corion, Lioe-Fee de Geus-Oei, Beatriz E. Adrada, Amy M. Fowler, Katie N. Hunt, S. Cheenu Kappadath, Patrick Pilkington, Lenka M. Pereira Arias-Bouda, Gaiane M. Rauch
Journal of Nuclear Medicine Technology Jun 2022, 50 (2) 103-110; DOI: 10.2967/jnmt.121.264204

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