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Review ArticleContinuing Education

Guidance on 177Lu-DOTATATE Peptide Receptor Radionuclide Therapy from the Experience of a Single Nuclear Medicine Division

Amanda Abbott, Christopher G. Sakellis, Eric Andersen, Yuji Kuzuhara, Lauren Gilbert, Kelly Boyle, Matthew H. Kulke, Jennifer A. Chan, Heather A. Jacene and Annick D. Van den Abbeele
Journal of Nuclear Medicine Technology September 2018, 46 (3) 237-244; DOI: https://doi.org/10.2967/jnmt.118.209148
Amanda Abbott
1Department of Imaging and Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
MS, CNMT, RT(N)(CT), PET
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Christopher G. Sakellis
1Department of Imaging and Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
2Department of Radiology, Brigham and Women’s Hospital, Boston, Massachusetts
3Harvard Medical School, Boston, Massachusetts
MD
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Eric Andersen
4Department of Environmental Health and Safety, Dana-Farber Cancer Institute, Boston, Massachusetts
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Yuji Kuzuhara
1Department of Imaging and Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
MHA, RT(N)(MR)(CT)
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Lauren Gilbert
1Department of Imaging and Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
CNMT, RT(N)(CT)
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Kelly Boyle
5Department of Adult Ambulatory Services, Nursing, and Imaging Services, Dana-Farber Cancer Institute, Boston, Massachusetts; and
MS, RN
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Matthew H. Kulke
3Harvard Medical School, Boston, Massachusetts
6Program in Neuroendocrine and Carcinoid Tumors, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
MD
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Jennifer A. Chan
3Harvard Medical School, Boston, Massachusetts
6Program in Neuroendocrine and Carcinoid Tumors, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
MD
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Heather A. Jacene
1Department of Imaging and Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
2Department of Radiology, Brigham and Women’s Hospital, Boston, Massachusetts
3Harvard Medical School, Boston, Massachusetts
MD
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Annick D. Van den Abbeele
1Department of Imaging and Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
2Department of Radiology, Brigham and Women’s Hospital, Boston, Massachusetts
3Harvard Medical School, Boston, Massachusetts
MD, FACR
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Article Information

vol. 46 no. 3 237-244
DOI 
https://doi.org/10.2967/jnmt.118.209148
PubMed 
30076245

Published By 
Society of Nuclear Medicine
Print ISSN 
0091-4916
Online ISSN 
1535-5675
History 
  • Received for publication April 6, 2018
  • Accepted for publication June 18, 2018
  • Published online September 6, 2018.

Article Versions

  • previous version (August 3, 2018 - 11:34).
  • You are viewing the most recent version of this article.
Copyright & Usage 
© 2018 by the Society of Nuclear Medicine and Molecular Imaging.

Author Information

  1. Amanda Abbott, MS, CNMT, RT(N)(CT), PET1,
  2. Christopher G. Sakellis, MD1–3,
  3. Eric Andersen4,
  4. Yuji Kuzuhara, MHA, RT(N)(MR)(CT)1,
  5. Lauren Gilbert, CNMT, RT(N)(CT)1,
  6. Kelly Boyle, MS, RN5,
  7. Matthew H. Kulke, MD3,6,
  8. Jennifer A. Chan, MD3,6,
  9. Heather A. Jacene, MD1–3 and
  10. Annick D. Van den Abbeele, MD, FACR1–3
  1. 1Department of Imaging and Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
  2. 2Department of Radiology, Brigham and Women’s Hospital, Boston, Massachusetts
  3. 3Harvard Medical School, Boston, Massachusetts
  4. 4Department of Environmental Health and Safety, Dana-Farber Cancer Institute, Boston, Massachusetts
  5. 5Department of Adult Ambulatory Services, Nursing, and Imaging Services, Dana-Farber Cancer Institute, Boston, Massachusetts; and
  6. 6Program in Neuroendocrine and Carcinoid Tumors, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
  1. For correspondence or reprints contact: Amanda Abbott, Department of Imaging, Dana-Farber Cancer Institute, 450 Brookline Ave., Boston, MA 02215. E-mail: amanda_abbott@dfci.harvard.edu
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Journal of Nuclear Medicine Technology: 46 (3)
Journal of Nuclear Medicine Technology
Vol. 46, Issue 3
September 1, 2018
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Guidance on 177Lu-DOTATATE Peptide Receptor Radionuclide Therapy from the Experience of a Single Nuclear Medicine Division
Amanda Abbott, Christopher G. Sakellis, Eric Andersen, Yuji Kuzuhara, Lauren Gilbert, Kelly Boyle, Matthew H. Kulke, Jennifer A. Chan, Heather A. Jacene, Annick D. Van den Abbeele
Journal of Nuclear Medicine Technology Sep 2018, 46 (3) 237-244; DOI: 10.2967/jnmt.118.209148
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  • Article
    • Abstract
    • 177LU-DOTATATE PRRT IN BRIEF
    • ROLES OF MULTIDISCIPLINARY TEAM MEMBERS
    • ORDERING AND RECEIPT OF 177LU-DOTATATE DOSE
    • PREPARATION OF TREATMENT ROOM AND RESTROOM
    • INFUSION OF AMINO ACIDS
    • PREPARATION OF 177LU-DOTATATE DOSE
    • INFUSION OF 177LU-DOTATATE
    • FURTHER RECOMMENDATIONS
    • CONCLUSION
    • DISCLOSURE
    • Acknowledgments
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • PDF

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Cited By...

  • 177Lu-Dotatate administration using an infusion pump or a peristaltic pump: comparison of two methods
  • A Rapid and Safe Infusion Protocol for 177Lu Peptide Receptor Radionuclide Therapy
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Keywords

  • Radionuclide Therapy
  • peptide receptor radionuclide therapy (PRRT)
  • nuclear medicine
  • 177Lu-DOTATATE
  • neuroendocrine tumor
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Guidance on 177Lu-DOTATATE Peptide Receptor Radionuclide Therapy from the Experience of a Single Nuclear Medicine Division
Amanda Abbott, Christopher G. Sakellis, Eric Andersen, Yuji Kuzuhara, Lauren Gilbert, Kelly Boyle, Matthew H. Kulke, Jennifer A. Chan, Heather A. Jacene, Annick D. Van den Abbeele
Journal of Nuclear Medicine Technology Sep 2018, 46 (3) 237-244; DOI: 10.2967/jnmt.118.209148

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