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Review ArticleTeaching Case Studies

False-Positive Findings on Dopamine Transporter SPECT Due to Therapeutic Dextroamphetamine and Amphetamine

Joseph A. Frankl, Sudeshna Bose and Phillip H. Kuo
Journal of Nuclear Medicine Technology June 2018, 46 (2) 149-150; DOI: https://doi.org/10.2967/jnmt.117.201558
Joseph A. Frankl
1College of Medicine, University of Arizona, Tucson, Arizona
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Sudeshna Bose
2Department of Neurology, University of Arizona, Tucson, Arizona
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Phillip H. Kuo
3Department of Medical Imaging, University of Arizona, Tucson, Arizona;
4Departments of Medicine and Biomedical Engineering, University of Arizona, Tucson, Arizona
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    FIGURE 1.

    (A) Decreased activity in left putamen (arrows) on dopamine transporter SPECT images obtained while patient was receiving dextroamphetamine and amphetamine supports diagnosis of Parkinson disease. (B) Typical normal dopamine transporter SPECT findings using same camera and reconstruction protocol.

  • FIGURE 2.
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    FIGURE 2.

    Dopamine transporter SPECT images obtained on different camera showed normalization after 7 wk without dextroamphetamine and amphetamine.

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Journal of Nuclear Medicine Technology: 46 (2)
Journal of Nuclear Medicine Technology
Vol. 46, Issue 2
June 1, 2018
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False-Positive Findings on Dopamine Transporter SPECT Due to Therapeutic Dextroamphetamine and Amphetamine
Joseph A. Frankl, Sudeshna Bose, Phillip H. Kuo
Journal of Nuclear Medicine Technology Jun 2018, 46 (2) 149-150; DOI: 10.2967/jnmt.117.201558

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False-Positive Findings on Dopamine Transporter SPECT Due to Therapeutic Dextroamphetamine and Amphetamine
Joseph A. Frankl, Sudeshna Bose, Phillip H. Kuo
Journal of Nuclear Medicine Technology Jun 2018, 46 (2) 149-150; DOI: 10.2967/jnmt.117.201558
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Keywords

  • dopamine transporter
  • single-photon positron emission tomography
  • ioflupane
  • Parkinson disease
  • amphetamine
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