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Research ArticleImaging

Validation of a Single-Time-Point Measurement of Total Abdominal Counts to Simplify Small Bowel and Colon Transit Analyses

Alan H. Maurer, Rahul Parupalli, Perry Orthey and Henry P. Parkman
Journal of Nuclear Medicine Technology December 2016, 44 (4) 239-242; DOI: https://doi.org/10.2967/jnmt.116.183368
Alan H. Maurer
1Department of Radiology, Section of Nuclear Medicine and Molecular Imaging, Lewis Katz School of Medicine at Temple University Hospital, Philadelphia, Pennsylvania; and
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Rahul Parupalli
2Department of Internal Medicine Gastroenterology Section, Lewis Katz School of Medicine at Temple University Hospital, Philadelphia, Pennsylvania
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Perry Orthey
2Department of Internal Medicine Gastroenterology Section, Lewis Katz School of Medicine at Temple University Hospital, Philadelphia, Pennsylvania
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Henry P. Parkman
2Department of Internal Medicine Gastroenterology Section, Lewis Katz School of Medicine at Temple University Hospital, Philadelphia, Pennsylvania
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Article Figures & Data

Figures

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  • FIGURE 1.
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    FIGURE 1.

    Anterior and posterior 111In-DTPA images of abdomen are shown with examples of large rectangular regions of interest used to obtain total abdominal counts for calculation of geometric mean and decay-corrected total abdominal counts for all time points. There is small time point–to–time point variation in total abdominal counts; however, variation from mean is always less than 10% (Table 2).

  • FIGURE 2.
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    FIGURE 2.

    Orientation and regions shown are same as in Figure 1, however, this figure shows example of patient in whom there is mild increase in total abdominal counts over course of 6 h of imaging.

  • FIGURE 3.
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    FIGURE 3.

    Orientation and regions shown are same as in Figure 1, but in this case there is mild decrease in total abdominal counts over course of 6 h of imaging.

Tables

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    TABLE 1

    Patient Demographics

    Patient no.Age (y)SexWeight (kg)Height (cm)Body surface area (m2), Du Bois method
    137F129.5167.62.33
    250M88.6182.92.11
    351F53.2152.41.49
    468F65.0157.51.66
    557F66.4154.91.65
    624F46.8170.21.53
    767F111.4172.72.23
    833F66.4165.11.73
    959F97.7167.61.75
    1030F51.4167.61.57
    1135F86.4170.21.98
    1252M65.9167.61.74
    1328F57.7154.91.56
    1452F66.4162.61.71
    1537F65.9162.61.71
    1652F58.2165.11.64
    1752F58.2162.61.62
    1851F62.7165.11.69
    1940F111.4157.52.08
    2046F80.0172.71.94
    2145F90.9165.11.98
    2235F50.0165.11.53
    2368F79.1177.81.97
    2428F65.0160.01.68
    2551M54.1182.91.71
    2620M55.9165.11.61
    2768F47.3162.61.59
    2840F50.0157.51.48
    2969M83.2177.82.01
    3040F41.8157.51.37
    • View popup
    TABLE 2

    Summary of Measured Total Abdominal Counts (Kcounts/min) for All Patients and All Time Points

    Time point
    Patient no.060120180240300360MeanSDCoefficient of variationSlope of regression line
    121.8121.5321.9821.5721.7621.7623.0321.920.512.34%0.002
    224.6722.9321.2020.9021.3723.2823.4922.551.416.27%−0.002
    334.4232.0631.5831.1330.7530.7833.8132.081.484.60%−0.003
    417.7716.8516.6516.8416.3416.6616.2816.770.492.94%−0.003
    525.3725.0826.2525.7425.9125.8926.0725.760.411.58%0.002
    625.0224.5923.8924.4624.1925.3624.9424.640.512.06%0.001
    722.7120.8920.8620.0319.1021.5421.9621.011.215.74%−0.002
    822.5522.1322.3222.3422.8823.8523.0722.730.592.61%0.003
    927.1326.5526.8226.3825.7326.1726.0126.400.481.82%−0.003
    1017.0616.3016.4916.0915.1915.1615.2415.930.754.70%−0.005
    1124.0724.8823.7524.5124.6123.9424.3024.290.401.65%0.000
    1219.6520.0719.4219.6319.5919.1419.5619.580.281.43%−0.001
    1316.4616.9917.1917.1717.2418.0518.1917.330.603.48%0.004
    1423.2022.3121.8822.7622.3423.3422.4122.610.522.31%0.000
    1522.0620.5520.0419.8020.1419.7820.1020.350.803.91%−0.004
    1621.9022.3122.3622.7023.1122.2423.3822.570.522.31%0.003
    1723.3121.9223.1023.0523.9223.8223.6823.260.682.93%0.003
    1818.8918.8318.3718.5719.4020.0219.1619.030.552.91%0.003
    1918.9119.6018.9619.2918.8219.1419.2119.130.271.39%0.000
    2016.1515.8214.7614.3213.9213.9014.4314.760.896.06%−0.006
    2125.3924.3423.5023.8222.7022.9523.5423.750.903.80%−0.005
    2223.8122.5721.6921.6920.8921.0021.0121.811.064.86%−0.007
    2314.8815.4414.4014.7114.0515.1314.8714.780.463.10%−0.001
    2417.7618.6618.7218.9718.9418.8219.5918.780.542.90%0.004
    2519.9420.5020.2520.3520.4519.9720.1520.230.221.09%0.000
    2620.8018.7418.2318.0418.1317.8517.7418.501.065.74%−0.007
    2710.3710.119.759.7410.399.529.919.970.333.34%−0.001
    2814.0813.1712.9912.3612.9413.6713.3513.220.554.18%−0.001
    2922.9421.8421.8021.6521.6221.7422.8222.060.572.57%0.000
    3022.3821.1020.5520.8921.3120.5319.7520.930.813.89%−0.005
    Mean21.1820.6220.3320.3220.2620.5020.7020.560.663.28%−0.001
    P0.5930.9540.8370.8320.7900.9590.9020.095
    PCC0.9780.9940.9960.9950.9900.9900.991SD, 0.003
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Journal of Nuclear Medicine Technology: 44 (4)
Journal of Nuclear Medicine Technology
Vol. 44, Issue 4
December 1, 2016
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Validation of a Single-Time-Point Measurement of Total Abdominal Counts to Simplify Small Bowel and Colon Transit Analyses
Alan H. Maurer, Rahul Parupalli, Perry Orthey, Henry P. Parkman
Journal of Nuclear Medicine Technology Dec 2016, 44 (4) 239-242; DOI: 10.2967/jnmt.116.183368
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Validation of a Single-Time-Point Measurement of Total Abdominal Counts to Simplify Small Bowel and Colon Transit Analyses
Alan H. Maurer, Rahul Parupalli, Perry Orthey, Henry P. Parkman
Journal of Nuclear Medicine Technology Dec 2016, 44 (4) 239-242; DOI: 10.2967/jnmt.116.183368

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