Article Figures & Data
Figures
- FIGURE 1.
Molecular structure of 99mTc-tilmanocept. It is composed of a dextran backbone to which multiple units of mannose and DTPA are attached. DTPA units serve as attachment sites for radioactive labeling with 99mTc. Mannose units provide a molecular mechanism by which 99mTc-tilmanocept binds to CD206 receptor specific to reticuloendothelial cells.
- FIGURE 2.
Squamous cell carcinoma in floor of mouth. 99mTc-tilmanocept was injected at tumor site, and anterior cervical nodes were visualized bilaterally. ANT = anterior; LAT = lateral.
- FIGURE 3.
Cancer in right breast. After periareolar intradermal injection of 99mTc-tilmanocept in right upper outer quadrant, sentinel node was identified in right axilla. ANT = anterior; LAT = lateral.
- FIGURE 4.
Melanoma in right arm. After intradermal injection of 99mTc-tilmanocept around lesion, sentinel node was identified in right axilla.
Jump to section
Related Articles
Cited By...
- CD206+ macrophages are relevant non-invasive imaging biomarkers and therapeutic targets in experimental lung fibrosis
- Tumor Immune Cell Targeting Chimeras (TICTACs) For Targeted Depletion of Macrophage-Associated Checkpoint Receptors
- Sentinel Lymph Node Biopsy in Breast Cancer with 99mTc-Tilmanocept: A Multicenter Study on Real-Life Use of a Novel Tracer
- 99mTc-Tilmanocept Versus 99mTc-Sulfur Colloid in Lymphoscintigraphy: Sentinel Lymph Node Identification and Patient-Reported Pain
- Use of 99mTc-Tilmanocept as a Single Agent for Sentinel Lymph Node Identification in Breast Cancer: A Retrospective Pilot Study