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Research ArticleIMAGING

Detection of 90Y Extravasation by Bremsstrahlung Imaging for Patients Undergoing 90Y-Ibritumomab Tiuxetan Therapy

Stephanie M. Rhymer, J. Anthony Parker and Matthew R. Palmer
Journal of Nuclear Medicine Technology December 2010, 38 (4) 195-198; DOI: https://doi.org/10.2967/jnmt.110.077354
Stephanie M. Rhymer
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J. Anthony Parker
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Matthew R. Palmer
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  • FIGURE 1.
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    FIGURE 1.

    Coronal section from 111In SPECT/CT study showing slice through chest and abdomen of patient 7 d after receiving 111In injection. Activity is fairly uniform throughout soft tissue but is markedly concentrated in liver.

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    FIGURE 2.

    Phantom arrangement consisted of torso phantom with lung and liver inserts, and adjacent cylindric arm phantom held in arm rest. The 7 × 11 cm absorbent patch is visible on superior surface of cylinder.

  • FIGURE 3.
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    FIGURE 3.

    Energy window settings used for imaging bremsstrahlung photons from 90Y in presence of 111In. Window samples photons between lead x-ray peak and 171-keV photopeak from 111In.

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    FIGURE 4.

    Images acquired with MEGP and HEGP collimators from phantom arrangement affixed with 8.3- and 26.9-MBq patches.

  • FIGURE 5.
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    FIGURE 5.

    Average counts per pixel within regions of interest placed over patch and background for 3 patches containing 90Y in varying concentrations for images acquired with MEGP (A) and HEGP (B) collimators. (C) Patch contrast calculated for MEGP and HEGP collimators.

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Journal of Nuclear Medicine Technology: 38 (4)
Journal of Nuclear Medicine Technology
Vol. 38, Issue 4
December 1, 2010
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Detection of 90Y Extravasation by Bremsstrahlung Imaging for Patients Undergoing 90Y-Ibritumomab Tiuxetan Therapy
Stephanie M. Rhymer, J. Anthony Parker, Matthew R. Palmer
Journal of Nuclear Medicine Technology Dec 2010, 38 (4) 195-198; DOI: 10.2967/jnmt.110.077354

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Detection of 90Y Extravasation by Bremsstrahlung Imaging for Patients Undergoing 90Y-Ibritumomab Tiuxetan Therapy
Stephanie M. Rhymer, J. Anthony Parker, Matthew R. Palmer
Journal of Nuclear Medicine Technology Dec 2010, 38 (4) 195-198; DOI: 10.2967/jnmt.110.077354
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