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Journal of Nuclear Medicine Technology

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OtherPharmacy

Kinevac Stability After Reconstitution with Sodium Chloride Injection USP, 0.9%

Latisha T. Littleton, Bader B. Fileta, Robert Massey and Timothy I. Wood
Journal of Nuclear Medicine Technology March 2009, 37 (1) 57-59; DOI: https://doi.org/10.2967/jnmt.108.050732
Latisha T. Littleton
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Bader B. Fileta
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Robert Massey
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Timothy I. Wood
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    FIGURE 1. 

    Sincalide peptide structure.

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    FIGURE 2. 

    Representative automatically scaled chromatographs with water and Kinevac peaks labeled. Triangles represent peak boundaries for area integration. (A) Kinevac reconstituted in sterile water and (B) Kinevac reconstituted in 0.9% sodium chloride. Third peak in B results from detection of sodium chloride in 0.9% sodium chloride (unlabeled).

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    TABLE 1

    Stability 8 Hours After Reconstitution Measured as Percentage of Time Zero Kinevac Concentration Remaining

    Trial no.Sample A: sterile waterSample B: 0.9% sodium chloride
    192.7074.80
    290.2082.40
    385.8077.70
    490.2085.30
    Average ± SD89.73 ± 2.4980.05 ± 4.07
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Journal of Nuclear Medicine Technology: 37 (1)
Journal of Nuclear Medicine Technology
Vol. 37, Issue 1
March 2009
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Kinevac Stability After Reconstitution with Sodium Chloride Injection USP, 0.9%
Latisha T. Littleton, Bader B. Fileta, Robert Massey, Timothy I. Wood
Journal of Nuclear Medicine Technology Mar 2009, 37 (1) 57-59; DOI: 10.2967/jnmt.108.050732

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Kinevac Stability After Reconstitution with Sodium Chloride Injection USP, 0.9%
Latisha T. Littleton, Bader B. Fileta, Robert Massey, Timothy I. Wood
Journal of Nuclear Medicine Technology Mar 2009, 37 (1) 57-59; DOI: 10.2967/jnmt.108.050732
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