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OtherIMAGING

Optimal 57Co Flood Source Activity and Acquisition Time for Lymphoscintigraphy Localization Images

Martha V. Mar, Renee L. Dickinson, William D. Erwin and Richard E. Wendt
Journal of Nuclear Medicine Technology June 2008, 36 (2) 82-87; DOI: https://doi.org/10.2967/jnmt.107.047043
Martha V. Mar
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Renee L. Dickinson
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William D. Erwin
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Richard E. Wendt III
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  • FIGURE 1. 
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    FIGURE 1. 

    Modified anthropomorphic thorax breast phantom used to simulate breast lymphoscintigraphy injection-site uptake (A) and lymphatic drainage to 2 nodes (B).

  • FIGURE 2. 
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    FIGURE 2. 

    Different 57Co sources (activities of 37, 126, 184, 220, and 269 MBq) allowed visualization of both nodes with acquisition time of 3 min (A–D). Anterior localization images (1 and 2 min) did not show both nodes; however, both nodes were visible on lateral images (C and D).

  • FIGURE 3. 
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    FIGURE 3. 

    Node activities of 37 kBq were undetectable on anterior transmission images; however, they were visible on lateral transmission images using 126-MBq (3.41-mCi) 57Co flood source.

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    FIGURE 4. 

    Plot of contrast-to-noise ratio versus source activity and block thickness for 2 node strengths.

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    TABLE 1

    CNR Calculations for 2 Block Thicknesses: 10 cm (Thin Patient) and 20 cm (Average Patient)

    57Co source activity (MBq)Node 1 (total counts)Node 2 (total counts)Background (mean counts)No. of pixels in background ROICNR node 1CNR node 2
    10-cm-thick acrylic
     371695050.522741.4131.0
     1261585140.892727.3100.0
     1841765371.152726.090.8
     2201855822.002717.871.9
     2692135502.482717.859.0
    20-cm-thick acrylic
     371394690.352544.0155.6
     1261534420.422544.0133.2
     1841564710.622535.7115.7
     2201784800.812535.1102.2
     2691334830.852524.2100.2
    • CNR = contrast-to-noise ratio.

    • Node detectability for transmission imaging decreases with thinner patients.

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    TABLE 2

    Effective Dose Estimates for 57Co Source Activities Given Standard 3-Minute Transmission Scans

    57Co source activity (MBq)Measured exposure rate (μSv/h)Exposure for single view (μSv)Total for unilateral study (μSv)Total for bilateral study (μSv)
    37201.002.03.0
    126874.358.713.1
    1841135.6511.317.0
    2201457.2514.521.8
    2691788.9017.826.7
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Journal of Nuclear Medicine Technology: 36 (2)
Journal of Nuclear Medicine Technology
Vol. 36, Issue 2
June 2008
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Optimal 57Co Flood Source Activity and Acquisition Time for Lymphoscintigraphy Localization Images
Martha V. Mar, Renee L. Dickinson, William D. Erwin, Richard E. Wendt
Journal of Nuclear Medicine Technology Jun 2008, 36 (2) 82-87; DOI: 10.2967/jnmt.107.047043

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Optimal 57Co Flood Source Activity and Acquisition Time for Lymphoscintigraphy Localization Images
Martha V. Mar, Renee L. Dickinson, William D. Erwin, Richard E. Wendt
Journal of Nuclear Medicine Technology Jun 2008, 36 (2) 82-87; DOI: 10.2967/jnmt.107.047043
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