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OtherPROFESSIONAL DEVELOPMENT

Considerations for Setting Up an Order Entry System for Nuclear Medicine Tests

Narihiro Hara, Masahisa Onoguchi, Toshihiko Nishida, Minoru Honda, Osamu Houjou, Masaru Yuhi, Teruhiko Takayama and Jun Ueda
Journal of Nuclear Medicine Technology December 2007, 35 (4) 259-271; DOI: https://doi.org/10.2967/jnmt.106.039818
Narihiro Hara
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Masahisa Onoguchi
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Toshihiko Nishida
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Minoru Honda
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Osamu Houjou
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Masaru Yuhi
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Teruhiko Takayama
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Jun Ueda
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  • FIGURE 1. 
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    FIGURE 1. 

    (A) Example of workflow of usual operation by IHE. (B) Flows of order entry system.

  • FIGURE 2. 
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    FIGURE 2. 

    Construction process of order entry system (waterfall model/prototype model).

  • FIGURE 3. 
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    FIGURE 3. 

    Example: Setting between test item groups. Setting of confinement using each test item as the baseline subject. (A) MRI test. (B) Nuclear medical test. (C) Nuclear medical test and MRI test.

  • FIGURE 4. 
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    FIGURE 4. 

    Example: Appointed test frame. In case of setting of time series (A), it is possible to set the same frame from Monday through Friday during routine work. In case of setting groups (B), it is necessary to set frames based on an operation form for each day.

  • FIGURE 5. 
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    FIGURE 5. 

    Example: Methods of obtaining appointment for nuclear medical test in which setting of appointed test frame is conducted between groups. Setting of confinement: methods for obtaining groups between test items.

  • FIGURE 6. 
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    FIGURE 6. 

    Example: Methods for obtaining appointment of nuclear medical test in group setting and MRI test in time series setting. Setting of confinement: methods for obtaining groups between test items.

  • FIGURE 7. 
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    FIGURE 7. 

    Flow from introduction to operation (outline).

Tables

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    TABLE 1

    Subsystem Design of Nuclear Scanning

    Time requiredPresence or absence of start from time appointed
    Group classificationTest item (NM)Collecting timeInjection time
    99mTc drug pro.gThyroid (99mTcO4−)30—○
    Parathyroid (99mTc-MIBI)30—○
    Salivary gland (99mTcO4−)30—○
    Brain (99mTc-ECD)30—○
    Head vein angiogram (99mTcO4−)30—○
    Trunk vein angiogram (99mTcO4−)30—○
    Upper limb (right) vein angiogram (99mTcO4−)30—○
    Upper limb (left) vein angiogram (99mTcO4−)30—○
    Pelvic vein angiogram (99mTcO4−)30—○
    Lower limb vein angiogram (99mTcO4−)30—○
    Head artery angiogram (99mTcO4−)30—○
    Trunk artery angiogram (99mTcO4−)30—○
    Upper limb (right) artery angiogram (99mTcO4−)30—○
    Upper limb (left) artery angiogram (99mTcO4−)30—○
    Pelvic artery angiogram (99mTcO4−)30—○
    Lower limb artery angiogram (99mTcO4−)30—○
    Bone drug pro.gBone adult/whole body (99mTc-HMDP)—10×
    Bone child/whole body (99mTc-HMDP)—10×
    67Ga drug pro.g67Ga adult/whole body (67Ga-citrate)—10×
    67Ga child/whole body (67Ga-citrate)—10×
    131I drug pro.gAdosterol (131I-adosterol)—10×
    Pheo scinitigraphy (131I-Pheo-MIBG)—10×
    201TI drug pro.gThyroid (201TICI)30—○
    Tumor (201TICI)30—○
    Myocardial blood flow at resting (201TICI)30—○
    Intake rate in thyroid drug pro.gIntake rate in thyroid (Na123I capsule)—10×
    99mTc + 67Ga drug pro.gBone+67Ga adult/whole body (99mTc-HMDP+67Ga-citrate)—10×
    Bone+67Ga child/whole body (99mTc-HMDP+67Ga-citrate)—10×
    123I drug pro.gMyocardial fatty acid metabolism (123I-BMIPP)40○
    Myocardial sympathetic nerve activity (123I-MIBG)40○
    Myocardial drug pro.gMyocardial blood flow at resting (99mTc-MIBI)—10×
    Myocardial blood flow movement (99mTc-TF)60—○
    Myocardial blood flow movement (201TICI)60—○
    Myocardial blood flow movement drug product (99mTc-TF)50—○
    Myocardial pool (99mTc-HAS-D)60—○
    Respiratory system drug pro.gLung blood flow (99mTc-MAA)30—○
    Lung ventilation (81mKr gas)30—○
    CBF drug pro.gCBF (123I-IMP)60—○
    Load of CBF (123I-IMP)120—○
    Digestive system drug pro.gLiver function (99mTc-GSA)30—○
    Liver/biliary tract (99mTc-PMT)30—○
    Liver (99mTc-Sn-colloid)30—○
    Spleen (99mTc-Sn-colloid)30—○
    Gastrointestinal bleeding (99mTc-HAS-D)60—○
    Ectopic gastic mucosa (99mTcO4−)60—○
    Urinary system drug pro.gRenal function/RPF (99mTc-MAG3)30—○
    Renal function/GFR (99mTc-DTPA)30—○
    Kidney (99mTc-DMSA)30—○
    111In drug pro.gBrain tank (111lnCl3)—10×
    Encephalon (111ln-DTPA)—10×
    Hematopoietic organ drug pro.gAmount of circulating blood10—○
    Erythrocyte life span10—○
    Later collection groupAdosterol at a later date—30×
    67Ga photograph adult at a later date—60×
    Intake rate in thyroid at a later date—30×
    Pheo scinitigraphy at a later date—30×
    Gastrointestinal bleeding at a later date—30×
    Bone marrow at a later date—60×
    Brain tank at a later date—60×
    • pro.g = product group; 99mTcO4− = 99mTc-pertechnetate; 99mTc-MIBI = 99mTc-methoxyisobutylisonitrile; 99mTc-ECD = 99mTc-ethyl cysteinate dimer; 99mTc-TF = 99mTc-tetrofosmin; 99mTc-HAS-D = 99mTc-diethylenetriamine pentaacetic acid human serum albumin; 99mTc-HAS-D = 99mTc-diethylenetriamine pentaacetic acid human serum albumin; 99mTc-MMA = 99mTc-macroaggretated albumin; 81mKr gas = krypton-81m gas; 99mTc-GSA = 99mTc-galactosyl human serum albumin; 99mTc-PMT = 99mTc-Sn-N-pyridoxyl-5-methyltryptophan; 99mTc-Sn-colloid = 99mTc-stannous-colliod; 99mTc-MAG3 = 99mTc-mercaptoacetyltriglycine; GFR = glomerular filtration rate; 99mTc-DTPA = 99mTc-diethylenetriaminepentaacetic acid; 99mTc-DMSA = 99mTc-dimercaptosuccinic acid; 111InCl3 = 111In-chloride; 111In-DTPA = 111In-diethylenetriaminepentaacetic acid; NM = nuclear medicine.

    • View popup
    TABLE 2

    Confined Setting of Test Items Between Groups

    Confined values between MRI tests (total set number: 180)
    Baseline test items (MRI: 90 items)Subject group (MRI: 2 sets)Time required for testsSet valueConfined value
    MRI head plainMRI plain pho.g10 minAbsence10 min
    MRI contrast pho.g10 minAbsence10 min
    MRI head contrastMRI plain pho.g20 minAbsence20 min
    MRI contrast pho.g20 min1 d1 d 20 min
    Confined values between NM tests (total set number: 1,824)
    Baseline test items (NM: 57 items)Subject group (NM: 16 sets)Time required for testsSet valueConfined value
    PastFuturePastFuture
    Thyroid99mTc drug pro.g30 min2 d2 d2 d 30 min2 d 30 min
    (99mTcO4−)Bone drug pro.g30 min2 d2 d2 d 30 min2 d 30 min
    67Ga drug pro.g30 min4 d4 d4 d 30 min4 d 30 min
    Bone adult/whole body99mTc drug pro.g10 min2 d2 d2 d 10 min2 d 10 min
    (99mTc-HMDP)Bone drug pro.g10 min2 d2 d2 d 10 min2 d 10 min
    67Ga drug pro.g10 min4 d4 d4 d 10 min4 d 10 min
    67Ga adult/whole body99mTc drug pro.g10 min4 d4 d4 d 10 min4 d 10 min
    (67Ga-citrate)Bone drug pro.g10 min2 d4 d2 d 10 min4 d 10 min
    67Ga drug pro.g10 min6 d6 d6 d 10 min6 d 10 min
    Confined values between NM tests and MRI tests (total set number: 1,554)
    Baseline test items (NM: 57 items) (MRI: 90 items)Subject group (MRI: 2 sets) (NM: 16 sets)Time required for testsSet valueConfined value
    ThyroidMRI plain pho.g30 min1 h1 h 30 min
    (99mTc-O4−)MRI contrast pho.g30 min1 h1 h 30 min
    Bone adult/whole bodyMRI plain pho.g10 minAbsence10 min
    (99mTc-HMDP)MRI contrast pho.g10 minAbsence10 min
    67Ga adult/whole bodyMRI plain pho.g10 minAbsence10 min
    (67Ga-citrate)MRI contrast pho.g10 minAbsence10 min
    MRI head plain99mTc drug pho.g10 min1 h1 h 10 min
    Bone drug pro.g10 minAbsence10 min
    67Ga drug pro.g10 minAbsence10 min
    MRI head contrast99mTc drug pro.g20 min1 h1 h 20 min
    Bone drug pro.g20 minAbsence10 min
    67Ga drug pro.g20 minAbsence10 min
    • pho.g = photography group; NM = nuclear medicine; pro.g = product group.

    • View popup
    TABLE 3

    Setting of Confined Values Between Groups

    Confined values between MRI tests (total set number: 4)
    Baseline group (MRI: 2 settings)Subject group (NM: 2 settings)Confined value
    MRI plain pho.gMRI plain pho.g1 h
    MRI contrast pho.g1 h
    MRI contrast pho.gMRI plain pho.g1 h
    MRI contrast pho.g1 d
    Confined values between NM tests (total set number: 512)
    Baseline group (NM: 16 settings)Subject group (NM: 16 settings)Confined value
    PastFuture
    99mTc drug pro.g99mTc drug pro.g2 d2 d
    Bone drug pro.g2 d2 d
    67Ga drug pro.g4 d4 d
    Bone drug pro.g99mTc drug pro.g2 d2 d
    Bone drug pro.g2 d2 d
    67Ga drug pro.g4 d4 d
    67Ga drug pro.g99mTc drug pro.g2 d4 d
    Bone drug pro.g2 d4 d
    67Ga drug pro.g6 d6 d
    Confined values between NM tests and MRI tests (total set number: 64)
    Baseline group (NM: 16 settings) (MRI: 2 settings)Subject group (MRI: 2 settings) (NM: 16 settings)Confined value
    99mTc drug pro.gMRI plain pho.g1 h
    MRI contrast pho.g1 h
    Bone drug pro.gMRI plain pho.g1 h
    MRI contrast pho.g1 h
    MRI plain pho.g99mTc drug pro.g1 h
    Bone drug pro.g1 h
    MRI contrast pho.g99mTc drug pro.g1 h
    Bone drug pro.g1 h
    • NM = nuclear medicine; pho.g = photography group; pro.g = product group.

    • View popup
    TABLE 4

    Setting of Confinement Between Test Items

    Confined values between MRI tests (total set number: 8,100)
    Baseline test items (MRI: 90 items)Subject group (MRI: 90 setting)Time required for testsSet valueConfined value
    MRI head plainMRI head plain10 min1 h1 h 10 min
    MRI pituitary plain10 minAbsence10 min
    MRI accesory sinus cavity plain10 minAbsence10 min
    MRI head contrast20 minAbsence20 min
    MRI pituitary contrast20 minAbsence20 min
    MRI head contrastMRI head plain20 minAbsence20 min
    MRI pituitary plain20 minAbsence20 min
    MRI head contrast20 min1 d1 d 20 min
    MRI pituitary contrast20 min1 d1 d 20 min
    MRI accesory sinus cavity contrast20 min1 d1 d 20 min
    Confined values between NM tests (total set number: 6,498)
    Baseline test items (NM: 57 items)Subject group (NM: 57 setting)Time required for testsSet valueConfined value
    PastFuturePastFuture
    Thyroid (99mTcO4−)Thyroid (99mTcO4−)30 min2 d2 d2 d 30 min2 d 30 min
    Bone adult/whole body (99mTc-HMDP)30 min2 d2 d2 d 30 min2 d 30 min
    67Ga adult/whole body (67Ga-citrate)30 min4 d4 d4 d 30 min4 d 30 min
    Bone adult/whole bodyThyroid (99mTcO4−)10 min2 d2 d2 d 10 min2 d 10 min
    (99mTc-HMDP)Bone adult/whole body (99mTc-HMDP)10 min2 d2 d2 d 10 min2 d 10 min
    67Ga adult/whole body (67Ga-citrate)10 min4 d4 d4 d 10 min4 d 10 min
    67Ga adult/whole bodyThyroid (99mTcO4−)10 min4 d4 d4 d 10 min4 d 10 min
    (67Ga-citrate)Bone adult/whole body (99mTc-HMDP)10 min4 d4 d4 d 10 min4 d 10 min
    67Ga adult/whole body (67Ga-citrate)10 min6 d6 d6 d 10 min6 d 10 min
    Confined values between NM tests and MRI tests (total set number: 10,260)
    Baseline test items (NM: 57 items) (MRI: 90 items)Subject group (MRI: 90 setting) (NM: 57 setting)Time required for testsSet valueConfined value
    Thyroid (99mTcO4−)MRI head plain30 min1 h1 h 30 min
    MRI head angiogram plain30 min1 h1 h 30 min
    Bone adult/whole body (99mTc-HMDP)MRI head plain10 minAbsence10 min
    MRI head angiogram plain10 minAbsence10 min
    Ga adult/whole body (67Ga-citrate)MRI head plain10 minAbsence10 min
    MRI head angiogram plain10 minAbsence10 min
    MRI head plainBone adult/whole body (99mTc-HMDP)10 minAbsence10 min
    67Ga adult/whole body (67Ga-citrate)10 minAbsence10 min
    MRI head contrastBone adult/whole body (99mTc-HMDP)20 minAbsence20 min
    67Ga adult/whole body (67Ga-citrate)20 minAbsence20 min
    • NM = nuclear medicine.

    • View popup
    TABLE 5

    Test Items Corresponding to Appointed Test Frames of NM Tests

    Appointed test framesTest items
    Bone test frameBone adult/whole body (99mTc-HMDP)
    Bone child/whole body (99mTc-HMDP)
    Brain test frameCBF (123I-IMP)
    Load of CBF (123I-IMP)
    Brain (99mTc-ECD)
    Brain tank (111InCl3)
    Encephalon (111In-DTPA)
    Circulatory organ resting test frameMyocardial fatty acid metabolism (123I-BMIPP)
    Myocardial sympathetic nerve activity (123I-MIBG)
    Myocardial blood flow at resting (201TICI)
    Circulatory organ resting QGS test frameMyocardial blood flow at resting (99mTc-MIBI)
    Circulatory organ exercising test frameMyocardial blood flow movement (99mTc-TF)
    Myocardial blood flow movement (201TICI)
    Myocardial blood flow movement drug product (99mTc-TF)
    Urinary system test frameRenal function/RPF (99mTc-MAG3)
    Renal function/GFR (99mTc-DTPA)
    Kidney (99mTc-DMSA)
    Respiratory system test frameLung blood flow (99mTc-MAA)
    Lung ventilation (81mKr gas)
    Angiograph system test frameHead vein angiogram (99mTcO4−)
    Trunk vein angiogram (99mTcO4−)
    Upper limb (right) vein angiogram (99mTcO4−)
    Upper limb (left) vein angiogram (99mTcO4−)
    Pelvic vein angiogram (99mTcO4−)
    Lower limb vein angiogram (99mTcO4−)
    Head artery angiogram (99mTcO4−)
    Trunk artery angiogram (99mTcO4−)
    Upper limb (right) artery angiogram (99mTcO4−)
    Upper limb (left) artery angiogram (99mTcO4−)
    Pelvic artery angiogram (99mTcO4−)
    Lower limb artery angiogram (99mTcO4−)
    Bone + 67Ga test frameBone + 67Ga adult/whole body (99mTc-HMDP + 67Ga-citrate)
    Bone + 67Ga child/whole body (99mTc-HMDP + 67Ga-citrate)
    67Ga adult/whole body (67Ga-citrate)
    67Ga child/whole body (67Ga-citrate)
    Tumor (201TI) test frameTumor (201TICI)
    Digestive system test frameLiver function (99mTc-GSA)
    Liver/biliary tract (99mTc-PMT)
    Liver (99mTc-Sn-colloid)
    Endocrine test frameThyroid (99mTcO4−)
    Parathyroid (99mTc-MIBI)
    Salivary gland (99mTcO4−)
    Thyroid (201TICI)
    Pheo-scintigraphy test framePheo-scintigraphy (131I-Pheo-MIBG)
    Intake rate in thyroid test frameIntake rate in thyroid (Na123I capsule)
    Adosterol test frameAdosterol (131I-adosterol)
    Hematopoietic system test frameSpleen (99mTc-Sn-colloid)
    Amount of circulating blood
    Erythrocyte life span
    Nuclear medical test frame at a later dateAdosterol at a later date
    67Ga photograph adult at a later date
    Intake rate in thyroid at a later date
    Pheo-scintigraphy at a later date
    Gastrointestinal bleeding at a later date
    Bone marrow at a later date
    Brain tank at a later date
    Emergent test frameGastrointestinal bleeding (99mTc-HAS-D)
    Ectopic gastric mucosa (99mTcO4−)
    Myocardial pool (99mTc-HAS-D)
    Demand test frameAll test items
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Journal of Nuclear Medicine Technology: 35 (4)
Journal of Nuclear Medicine Technology
Vol. 35, Issue 4
December 2007
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Considerations for Setting Up an Order Entry System for Nuclear Medicine Tests
Narihiro Hara, Masahisa Onoguchi, Toshihiko Nishida, Minoru Honda, Osamu Houjou, Masaru Yuhi, Teruhiko Takayama, Jun Ueda
Journal of Nuclear Medicine Technology Dec 2007, 35 (4) 259-271; DOI: 10.2967/jnmt.106.039818

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Considerations for Setting Up an Order Entry System for Nuclear Medicine Tests
Narihiro Hara, Masahisa Onoguchi, Toshihiko Nishida, Minoru Honda, Osamu Houjou, Masaru Yuhi, Teruhiko Takayama, Jun Ueda
Journal of Nuclear Medicine Technology Dec 2007, 35 (4) 259-271; DOI: 10.2967/jnmt.106.039818
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