Abstract
Three traumatic skeletal fracture cases were investigated with technetium-99m- (99mTc) phytate, sulfur colloid, and methylene diphosphonate (MDP), to study the behavior of the radiopharmaceuticals at the fracture site. The radiopharmaceuticals were intravenously administered and imaging of the fracture site and its contralateral part was performed at 15 min and 1 hr postinjection for 99mTc-phytate and 99mTc-sulfur colloid and after 3 hr for 99mTc-MDP. It was observed that 99mTc-phytate shows significant uptake at the fracture site and continues to persist whereas 99mTc-sulfur colloid does not show any significant uptake. The 99mTc-phytate scans at the fracture site were similar to 99mTc-MDP scans. The possible mechanism of the unusual behavior of 99mTc-phytate is discussed.