Comparison of Radiometric Microbiologic Assay and Competitive Protein Binding Radioassay for Plasma and Red Blood Cell Folate Levels

Abstract

We compared the radiometric microbiologic assay with a commercially available competitive protein binding radioassay kit for plasma and red blood cell folate. The correlation coefficient between these two assays was r = 0.78 for plasma folate and r = 0.87 for red blood cell folate. The sensitivity of the radiometric microbiologic assay was 96% for red blood cell folate.