An Introduction to Na¹⁸F Bone Scintigraphy: Basic Principles, Advanced Imaging Concepts, and Case Examples

Dual-tracer acquisition: combined injection of ¹⁸F-FDG and ¹⁸F. (A) Two views of combined tracer showing soft-tissue, lytic bone, and osteoblastic bone lesions. Arrows point to small osteoblastic lesion in sacrum. (B and C) Fused CT and ¹⁸F-FDG/¹⁸F PET characterizing lesion (arrows) as small and osteoblastic in central body of S2. (D) CT image of B with fusion shows sclerotic nature of S2 lesion. Note sclerotic focus centrally within S2 body in lower left corner of CT image and same area on fused images. This area would probably not have been visualized on plain ¹⁸F-FDG scan.