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Research ArticlePearls and Pitfalls

Motion Artifacts in SPECT Myocardial Perfusion Imaging

Sara G. Johnson
Journal of Nuclear Medicine Technology June 2025, 53 (2) 138-139; DOI: https://doi.org/10.2967/jnmt.125.269853
Sara G. Johnson
Nuclear Medicine Service, Jennifer Moreno VA San Diego Healthcare System, San Diego, California
CNMT, NCT, FSNMMI-TS
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Myocardial perfusion imaging (MPI) with gated SPECT makes up approximately 40%–60% of procedures performed daily in nuclear medicine. More than 11 million MPI scans are performed annually in the United States (1). Today’s advanced SPECT technology, coupled with sophisticated cardiac software, continues to improve image quality, specificity, and sensitivity in detecting clinically relevant coronary artery disease (2,3).

THE “PITFALLS”

Artifacts commonly found in MPI can degrade image quality, which can lead to an inaccurate interpretation of the scan (3,4). Artifacts can be attributed to the patient, equipment, or technical factors. Patient motion is a common source of artifacts and will be the focus of this discussion.

Although some systems offer motion correction software, it is limited to correcting movements of up to 2 pixels. Patient motion exceeding this threshold can produce detectable artifacts that may be clinically significant, necessitating a repeat scan (3,5). Nuclear medicine technologists play a crucial role in managing patient motion, being responsible for comprehensive preparation before and during imaging to minimize movement. After image acquisition, an immediate review of the MPI study is essential to assess for motion and other technical factors. Best practice guidelines recommend repeating the scan when patient motion greater than 2 pixels is observed (2–5). However, the optimal approach is to prevent patient motion entirely whenever possible as this ensures the highest quality imaging results (2–5).

SUGGESTED “PEARLS” TO HELP REDUCE OR ELIMINATE PATIENT MOTION

Directions to the Patient

Provide the patient with a detailed description of the procedure, emphasizing the importance of not speaking or moving any part of the body during image acquisition.

Explain the scan’s importance in managing their CAD or suspected CAD. A well-informed patient is more likely to cooperate and tolerate any discomfort during imaging.

Emphasize the importance of staying awake during the scan because falling asleep can cause a change in the breathing pattern and consequently change the movement of the chest and heart motion. Also, explain that motion may be further exaggerated during sleeping if the patient snores, gasps, twitches, or inadvertently moves.

In casual conversation, determine if the patient is a singer. Although this sounds like an unusual topic of conversation, another breathing artifact may be encountered if the patient is a singer. Some singers are taught to breathe from their diaphragm to help them improve their breath support, resonance, and vocal control (6). This deep belly breathing can cause exaggerated motion in the chest. If possible, practice with the patient to encourage them to breathe normally and avoid deep belly breathing.

Patient Comfort

Take the time to ensure the patient’s comfort by utilizing support pillows under the knees, shoulder, arms, etc.; utilizing straps that may be used to support stiff arms or shoulders; and providing a warm blanket or no blanket as desired.

Additional Suggestions

Assess the patient for claustrophobia or anxiety to determine whether additional preparation is required before and during imaging. Before imaging, the patient may benefit from a “trial run.” Allow the patient to lie on the imaging table and experience the required body position and camera motion during acquisition. This trial run can be performed either before the start of the exam or days before the procedure. If the patient finds that the scan is intolerable, then contact with the referring physician may be required to obtain antianxiety medication on the day of the procedure. If the patient has been provided with antianxiety medication, the technologist should ensure that the appropriate dosing times correspond with both imaging times—rest and stress imaging.

Additional suggestions to support an anxious or claustrophobic patient include the following: (1) Keep as much of the patient’s head outside the scanner. An anxious patient will usually tolerate the scan better if the detectors are not directly over their head. However, the technologist must ensure enough of the chest is under the scanner to maintain the heart in the field of view. (2) Give the patient a verbal countdown to the scan’s end whenever possible. Turning the p-scope so the patient can see the scan duration timeline live on the monitor may also be beneficial. (3) Adjust the lights, covering the patient’s eyes, and/or providing music may also be beneficial in providing the patient with a calming environment to minimize anxiety and discomfort. (4) Eliminate the safety straps that may make some patients anxious; however, the technologist must be vigilant to ensure the patient does not move or is injured by falling off the table. (5) Have the technologist or a family member (preferred) support the patient by talking to them or holding their hand if CT is not performed during the procedure; however, the patient should understand that they must not speak or turn their head, which may introduce motion in the image. (6) Utilize prone imaging to help reduce the patient’s anxiety. This way the camera heads are not directly over the patient’s face. However, prone imaging can introduce additional artifacts and may make gating difficult. (7) Use upright imaging cameras, when available (e.g., Digirad Inc., CardiArc Ltd.), or semiupright cameras (D-SPECT, Spectrum Dynamics) which can significantly alleviate a patient’s anxiety as the patient is seated or semireclined and the detector is positioned at the chest rather than over the patient’s face. For the upright imaging cameras, the arms comfortably rest on the unit’s armrest, alleviating the need for the patient to stabilize the weight of their arm overhead. However, motion can still be noted with these upright imaging systems. The patients tend to sit up straight at the start of the imaging procedure, and as the scan proceeds, they may relax and slump down in the imaging chair. This motion can introduce an artifact into the image. One suggestion to avoid this slumping motion, after positioning the patient for imaging, is for the technologist to run both hands over the back of the patient’s neck and shoulders while encouraging the patient to relax. In this manner, the patient will be resting at the start of the exam and less likely to introduce motion by slumping down.

CONCLUSION

Patient motion during MPI imaging can adversely affect image quality and the study’s final interpretation. Nuclear medicine technologists can play an essential role in minimizing or eliminating motion where possible by using various tactics to enhance patient comfort and ensure that the best-quality scan is delivered to the provider for interpretation.

DISCLOSURE

No potential conflict of interest relevant to this article was reported.

Footnotes

  • Published online Apr. 1, 2025.

REFERENCES

  1. 1.↵
    1. Garcia EV,
    2. Klein LJ,
    3. Taylor AT
    . Clinical decision support systems in myocardial perfusion imaging. J Nucl Cardiol. 2014;21:427–439.
    OpenUrlPubMed
  2. 2.↵
    1. Burrell S,
    2. Macdonald A
    . Artifacts and pitfalls in myocardial perfusion imaging. J Nucl Med Technol. 2006;34:193–211.
    OpenUrlAbstract/FREE Full Text
  3. 3.↵
    1. Slomka PJ,
    2. Patton JA,
    3. Berman DS,
    4. Germano G
    . Advances in technical aspects of myocardial perfusion SPECT Imaging. J Nucl Cardiol. 2009;16:255–276.
    OpenUrlCrossRefPubMed
  4. 4.↵
    1. Matsumoto N,
    2. Berman DS,
    3. Kavanagh PB,
    4. et al
    . Quantitative assessment of motion artifacts and validation of a new motion-correction program for myocardial perfusion SPECT. J Nucl Med. 2001;42:687–694.
    OpenUrlAbstract/FREE Full Text
  5. 5.↵
    Interpretation and reporting of SPECT myocardial perfusion imaging. The Thoracic Key: Fastest Thoracic Insight engine website. https://thoracickey.com/interpretation-and-reporting-of-spect-myocardial-perfusion-imaging/#. Accessed February 20, 2025.
  6. 6.↵
    How to Sing from Your Diaphragm: 3 Simple singing tips. MasterClass, Arts & Entertainment website. https://www.masterclass.com/articles/how-to-sing-from-your-diaphragm. Accessed February 20, 2025.
  • Received for publication March 6, 2025.
  • Accepted for publication March 6, 2025.
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Journal of Nuclear Medicine Technology: 53 (2)
Journal of Nuclear Medicine Technology
Vol. 53, Issue 2
June 1, 2025
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Motion Artifacts in SPECT Myocardial Perfusion Imaging
Sara G. Johnson
Journal of Nuclear Medicine Technology Jun 2025, 53 (2) 138-139; DOI: 10.2967/jnmt.125.269853

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Motion Artifacts in SPECT Myocardial Perfusion Imaging
Sara G. Johnson
Journal of Nuclear Medicine Technology Jun 2025, 53 (2) 138-139; DOI: 10.2967/jnmt.125.269853
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