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OtherRadionuclide Therapy (JNMT)

ANALYSIS OF THE RADIOMETRY PERFORMED IN PATIENTS UNDERGOING RADIOACTIVE IODINE THERAPY

Pietro Paolo de Barros, Tatiane S C Camozzato, Tiago Jahn, Flávio Augusto Penna Soares, Letícia Machado da Silva, Jacqueline de Aguiar Soares and Marco Antonio Neiva Koslosky
Journal of Nuclear Medicine Technology November 2020, jnmt.120.246512; DOI: https://doi.org/10.2967/jnmt.120.246512
Pietro Paolo de Barros
1 Fed. Institute of Education, Science and Technology of Santa Catarina - IFSC, Florianópolis, Brazil;
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Tatiane S C Camozzato
1 Fed. Institute of Education, Science and Technology of Santa Catarina - IFSC, Florianópolis, Brazil;
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Tiago Jahn
2 Bionuclear, Florianópolis, Brazil
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Flávio Augusto Penna Soares
1 Fed. Institute of Education, Science and Technology of Santa Catarina - IFSC, Florianópolis, Brazil;
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Letícia Machado da Silva
1 Fed. Institute of Education, Science and Technology of Santa Catarina - IFSC, Florianópolis, Brazil;
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Jacqueline de Aguiar Soares
1 Fed. Institute of Education, Science and Technology of Santa Catarina - IFSC, Florianópolis, Brazil;
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Marco Antonio Neiva Koslosky
1 Fed. Institute of Education, Science and Technology of Santa Catarina - IFSC, Florianópolis, Brazil;
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Abstract

The treatment for differentiated thyroid cancer (DTC) consists of a thyroidectomy followed by radioactive iodine therapy (RIT), in which the patient remains in isolation until the exposure rate of the radioactive iodine reaches a certain limit. The present research intends to estimate the length of stay of patients subjected to RIT with radiometry analysis performed throughout the patient’s admission. Methods: Information such as age, gender, weight, height, prescribed activity, liquid intake, and the use of recombinant human thyrotropin (rhTSH) was gathered from a total of 204 patients with DTC, subjected to RIT. During the admission, the exposure rates were periodically measured. The data served as variables for a multiple regression, in which the coefficients and significance of each were verified as a function of the exposure rate. Results: The results showed that the length of stay, the administered activity, the intake volume of liquids, the use of rhTSH, and the patient’s weight impacted significantly on the dose rate. The average effective half-life of the 131I, considering all patients, was 12.61 ± 3.28 h, and the average time for their radiological release was 15.23 ± 5.50 h. Based on the results it was possible to develop a tool to estimate a patient’s length of stay and effective half-life times. Conclusion: The results can contribute to an optimization of the radiological protection of patients submitted to RIT, as well as allow better logistics of their admission, which can lead to more appropriate accommodation for the patient with a better use of resources.

  • Radionuclide Therapy
  • Half-life
  • Nuclear Medicine
  • Radiation protection
  • Therapy
  • iodine radioisotopes

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Journal of Nuclear Medicine Technology: 48 (4)
Journal of Nuclear Medicine Technology
Vol. 48, Issue 4
December 1, 2020
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ANALYSIS OF THE RADIOMETRY PERFORMED IN PATIENTS UNDERGOING RADIOACTIVE IODINE THERAPY
Pietro Paolo de Barros, Tatiane S C Camozzato, Tiago Jahn, Flávio Augusto Penna Soares, Letícia Machado da Silva, Jacqueline de Aguiar Soares, Marco Antonio Neiva Koslosky
Journal of Nuclear Medicine Technology Nov 2020, jnmt.120.246512; DOI: 10.2967/jnmt.120.246512

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ANALYSIS OF THE RADIOMETRY PERFORMED IN PATIENTS UNDERGOING RADIOACTIVE IODINE THERAPY
Pietro Paolo de Barros, Tatiane S C Camozzato, Tiago Jahn, Flávio Augusto Penna Soares, Letícia Machado da Silva, Jacqueline de Aguiar Soares, Marco Antonio Neiva Koslosky
Journal of Nuclear Medicine Technology Nov 2020, jnmt.120.246512; DOI: 10.2967/jnmt.120.246512
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Keywords

  • Radionuclide Therapy
  • Half-life
  • Nuclear Medicine
  • Radiation protection
  • Therapy
  • iodine radioisotopes
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