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Research ArticleImaging

Added Value of Digital over Analog PET/CT: More Significant as Image Field of View and Body Mass Index Increase

Shirin Hatami, Sarah Frye, Anna McMunn, Crystal Botkin, Razi Muzaffar, Kara Christopher and Medhat Osman
Journal of Nuclear Medicine Technology December 2020, 48 (4) 354-360; DOI: https://doi.org/10.2967/jnmt.120.244160
Shirin Hatami
1Doisy College of Health Sciences, Saint Louis University, St. Louis, Missouri
RT (R)(MR)(ARRT)(NMCT)
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Sarah Frye
1Doisy College of Health Sciences, Saint Louis University, St. Louis, Missouri
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Anna McMunn
2Saint Louis University Hospital, SSM Health, St. Louis, Missouri
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Crystal Botkin
1Doisy College of Health Sciences, Saint Louis University, St. Louis, Missouri
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Razi Muzaffar
3Division of Nuclear Medicine, Department of Radiology, Saint Louis University, St. Louis, Missouri; and
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Kara Christopher
4Saint Louis University Hospital, Cancer Center, St. Louis, Missouri
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Medhat Osman
3Division of Nuclear Medicine, Department of Radiology, Saint Louis University, St. Louis, Missouri; and
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Abstract

The digital PET/CT scanner with digital photon-counting technique promises a shorter scan time, improved small-lesion detectability, and reduced radiation dose for the PET and CT portions of the exam while improving image quality. Methods: In this single-institution retrospective review study, 84 participants who had undergone PET/CT on both analog and digital scanners were analyzed. The aim was to evaluate the impact of image field of view (FOV) and body mass index (BMI) on the digital compared with the analog PET/CT scanners. The participants were categorized into different groups based on their BMI. Total scan times, 18F-FDG doses, and dose–length products (DLP) were collected and compared. Image quality was also assessed by certified nuclear medicine physicians and graded on a scale from 1 to 5. Results: In the skull–to–mid-thigh FOVs, the digital scanner had a scan time shorter by 37% (P < 0.001), a 18F-FDG dose lower by 16% (P < 0.001), but only an 8% reduction in DLP (P = 0.2). In the head-to-toe FOV cases, the digital scanner showed reductions in scan time (33%; P < 0.001), 18F-FDG dose (13%; P < 0.001), and DLP (19%; P < 0.001). When BMI was accounted for, the digital scanner had a scan time shorter by 33% (P < 0.001), as well as a reduced DLP (P < 0.001) and 18F-FDG dose (P < 0.001), with the most prominent changes being in the overweight and obese participants. Image quality was also improved by the digital scanner, with a score of 4.5, versus 4.0 for the analog scanner. Conclusion: The digital scanner has a shorter scan time and lower DLP, requires a lower 18F-FDG dose, and provides improved image quality when compared with the analog scanner. The most impactful difference in scan time, DLP, and 18F-FDG dose were observed in obese and overweight participants.

  • scan time
  • DLP
  • weight-based dosing
  • BMI
  • digital

Footnotes

  • Published online Sep. 4, 2020.

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Journal of Nuclear Medicine Technology: 48 (4)
Journal of Nuclear Medicine Technology
Vol. 48, Issue 4
December 1, 2020
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Added Value of Digital over Analog PET/CT: More Significant as Image Field of View and Body Mass Index Increase
Shirin Hatami, Sarah Frye, Anna McMunn, Crystal Botkin, Razi Muzaffar, Kara Christopher, Medhat Osman
Journal of Nuclear Medicine Technology Dec 2020, 48 (4) 354-360; DOI: 10.2967/jnmt.120.244160

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Added Value of Digital over Analog PET/CT: More Significant as Image Field of View and Body Mass Index Increase
Shirin Hatami, Sarah Frye, Anna McMunn, Crystal Botkin, Razi Muzaffar, Kara Christopher, Medhat Osman
Journal of Nuclear Medicine Technology Dec 2020, 48 (4) 354-360; DOI: 10.2967/jnmt.120.244160
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Keywords

  • Scan time
  • DLP
  • weight-based dosing
  • BMI
  • Digital
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