Improved Accuracy of Amyloid PET Quantification with Adaptive Template–Based Anatomic Standardization

Y Tsubaki, T Kitamura, N Shimokawa… - Journal of Nuclear …, 2021 - Soc Nuclear Med
Amyloid PET noninvasively visualizes amyloid-β accumulation in the brain. Visual binary
reading is the standard method for interpreting amyloid PET, whereas objective quantitative …

Feasibility study of a PET-only amyloid quantification method: a comparison with visual interpretation

N Shimokawa, G Akamatsu, M Kadosaki… - Annals of Nuclear …, 2020 - Springer
Objective Visual evaluation is the standard for amyloid positron emission tomography (PET)
examination, though the result depends upon the physician's subjective review of the …

Clinical Performance Evaluation of an AI-powered Amyloid Brain PET Quantification Method

SK Kang, D Kim, SA Shin, H Choi, M Heo, JY Chung… - 2023 - Soc Nuclear Med
P528 Introduction: The aim of this study was to evaluate the clinical performance of
BTXBrain-Amyloid, an artificial intelligence (AI)-based software for quantifying amyloid …

Automated PET-only quantification of amyloid deposition with adaptive atlas and empirically pre-defined ROI template

G Akamatsu, Y Ikari, A Ohnishi, T Nishio, H Nishida… - 2016 - Soc Nuclear Med
239 Objectives Amyloid PET provides an important tool for the assessment of early and
differential diagnosis of Alzheimer's disease (AD) and is also used for screening of subjects …

Quantitative Brain Amyloid PET

WJ Jagust, VS Mattay, DM Krainak… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Since the development of amyloid tracers for PET imaging, there has been interest in
quantifying amyloid burden in the brains of patients with Alzheimer disease. Quantitative …

Semiquantitative approach to amyloid PET interpretation in clinical practice

D Petrover, L Giliberto, S Clouston, M Gordon… - 2021 - Soc Nuclear Med
1068 Introduction: β-Amyloid (Aβ) neuroimaging plays a vital role in in vivo detection of Aβ
accumulation in patients with cognitive impairment consistent with Alzheimer's disease …

[HTML][HTML] Automated semi-quantitative amyloid PET analysis technique without MR images for Alzheimer's disease

E Imabayashi, N Tamamura, Y Yamaguchi… - Annals of Nuclear …, 2022 - Springer
Objective Although beta-amyloid (Aβ) positron emission tomography (PET) images are
interpreted visually as positive or negative, approximately 10% are judged as equivocal in …

Comparing amyloid PET tracers and interpretation strategies: first results from the CAPTAINs study

G Bischof, P Bartenstein, H Barthel, B Van Berckel… - 2018 - Soc Nuclear Med
485 Objectives: Three Fluorine 18-labelled tracers are currently commercially available to
measure cerebral amyloid pathology to assist in the diagnosis of possible Alzheimer's …

[HTML][HTML] Quantification of amyloid PET for future clinical use: a state-of-the-art review

HG Pemberton, LE Collij, F Heeman, A Bollack… - European journal of …, 2022 - Springer
Amyloid-β (Aβ) pathology is one of the earliest detectable brain changes in Alzheimer's
disease (AD) pathogenesis. The overall load and spatial distribution of brain Aβ can be …

Fast and accurate amyloid brain PET quantification without MRI using deep neural networks

SK Kang, D Kim, SA Shin, YK Kim… - Journal of Nuclear …, 2023 - Soc Nuclear Med
This paper proposes a novel method for automatic quantification of amyloid PET using deep
learning–based spatial normalization (SN) of PET images, which does not require MRI or CT …