The Expanding Role of Nuclear Medicine and Molecular Imaging in Management of Neurodegenerative Disease

S Holbrook - Journal of Nuclear Medicine Technology, 2013 - Soc Nuclear Med
There has been tremendous excitement regarding biomarkers that provide in vivo
information on neurodegenerative diseases. Until now, diagnosis has been through clinical …

Future directions in molecular imaging of neurodegenerative disorders

H Barthel, VL Villemagne… - Journal of Nuclear …, 2022 - Soc Nuclear Med
The improvement of existing techniques and the development of new molecular imaging
methods are an exciting and rapidly developing field in clinical care and research of …

[HTML][HTML] 18F-labeled radiopharmaceuticals for the molecular neuroimaging of amyloid plaques in Alzheimer's disease

L Filippi, A Chiaravalloti, O Bagni… - American Journal of …, 2018 - ncbi.nlm.nih.gov
Alzheimer's disease (AD) is the most common cause of dementia in the elderly, with
tremendous impact on the affected individuals and the society. Definitive diagnosis can be …

Amyloid imaging with 18F-florbetaben in Alzheimer disease and other dementias

VL Villemagne, K Ong, RS Mulligan… - Journal of Nuclear …, 2011 - Soc Nuclear Med
Amyloid imaging with 18F-labeled radiotracers will allow widespread use, facilitating
research, diagnosis, and therapeutic development for Alzheimer disease. The purpose of …

Nuclear medicine investigations in dementia and Parkinsonism.

T Rus, J Jamšek, R Berlot, KŠ Popović, M Grmek… - 2020 - cabidigitallibrary.org
The incidence of neurodegenerative brain disorders presenting as dementia or
parkinsonism is increasing with population aging. Early and correct diagnosis is essential for …

Molecular Imaging in Neurology

S Vallabhajosula - Molecular Imaging and Targeted Therapy …, 2023 - Springer
Radioisotope-based molecular imaging (MI) techniques such as PET/CT and SPECT/CT
aim to integrate patient-specific and disease-specific molecular information with traditional …

[CITATION][C] Amyloid Imaging Progress at FDA

P Herscovitch - Journal of Nuclear Medicine, 2009 - Soc Nuclear Med
Arecent meeting convened by the US Food and Drug Administration (FDA) provides
optimism for the introduction of new molecular imaging agents for clinical use, particularly for …

[HTML][HTML] Amyloid-β imaging with PET in Alzheimer's disease: is it feasible with current radiotracers and technologies?

MC Moghbel, B Saboury, S Basu, SD Metzler… - European journal of …, 2012 - Springer
Although it afflicts an estimated 26.6 million people worldwide—a figure that is expected to
quadruple by 2050—Alzheimer's disease (AD) has yet to be fully understood etiologically …

Visual versus fully automated analyses of 18F-FDG and amyloid PET for prediction of dementia due to Alzheimer disease in mild cognitive impairment

T Grimmer, C Wutz, P Alexopoulos… - Journal of Nuclear …, 2016 - Soc Nuclear Med
Biomarkers of Alzheimer disease (AD) can be imaged in vivo and can be used for diagnostic
and prognostic purposes in people with cognitive decline and dementia. Indicators of …

An overview of PET neuroimaging

I Nasrallah, J Dubroff - Seminars in nuclear medicine, 2013 - Elsevier
Over the past 35 years or so, PET brain imaging has allowed powerful and unique insights
into brain function under normal conditions and in disease states. Initially, as PET …