Influential Factors in the Preparation of 68Ga-DOTATATE

P Fang, MS Jacobson, JC Hung - Journal of Nuclear Medicine …, 2020 - Soc Nuclear Med
Acceptable and reproducible radiochemical purity (RP) for 68Ga-DOTATATE was difficult to
obtain with the NETSPOT kit because the manufacturer instructions lacked details on the …

[PDF][PDF] Optimized production and quality control of 68Ga-DOTATATE

A Aghanejad, AR Jalilian, S Maus… - Iranian Journal of …, 2016 - irjnm.tums.ac.ir
Introduction: Optimized production and quality control of 68Ga-DOTATATE as an efficient
and preferable PET radiotracer for somatostatin receptor imaging in neuroendocrine tumors …

Rapid instant Thin-Layer chromatography system for determining the radiochemical purity of 68Ga-DOTATATE

MG Bornholdt, KM Woelfel, P Fang… - Journal of Nuclear …, 2018 - Soc Nuclear Med
The objective of this study was to develop instant thin-layer chromatography (ITLC)
conditions for the determination of radiochemical purity of 68Ga-DOTATATE in a shorter time …

Optimal buffer choice of the radiosynthesis of 68Ga–Dotatoc for clinical application

M Bauwens, R Chekol, H Vanbilloen… - Nuclear medicine …, 2010 - journals.lww.com
Objectives 68 Ga–Dotatoc has become the PET radiopharmaceutical of choice for the
diagnosis and treatment follow-up of neuroendocrine tumours. 68 Ga–Dotatoc is prepared …

[PDF][PDF] Development of freeze-dried DOTMP kits for labeling with 68Ga

JC Lim, SM Choi, EH Cho, SY Lee, SH Dho, SY Kim - J Radiat Indus, 2015 - ksri.kr
Lyophilized dotMP kits were prepared using dotMP, ammonium acetate, and ascorbic acid.
the 68Ga-dotMP was prepared by incubating the kit dissolved in 0.5 ml of concentrated …

Development of a simple kit-based method for preparation of pharmaceutical-grade 68Ga-DOTATOC

M Asti, M Iori, PC Capponi, S Rubagotti… - Nuclear Medicine …, 2015 - journals.lww.com
Materials and methods A fraction of the eluate of two different 68 Ge/68 Ga generators was
directly injected into a vial prefilled with precursor, buffer and scavenger (the prototype of a …

Validation of 68Ge/68Ga generator processing by chemical purification for routine clinical application of 68Ga-DOTATOC

M Asti, G De Pietri, A Fraternali, E Grassi… - Nuclear medicine and …, 2008 - Elsevier
INTRODUCTION: Imaging of somatostatin receptor expressing tumours has been greatly
enhanced by the use of 68Ga-DOTATOC and PET/CT. METHODS: In this work, a purification …

Ethanol-based post-processing of generator-derived 68Ga toward kit-type preparation of 68Ga-radiopharmaceuticals

E Eppard, M Wuttke, PL Nicodemus… - Journal of nuclear …, 2014 - Soc Nuclear Med
Post-processing by means of a cation-exchanger–based protocol is an efficient strategy for
purification and concentration of generator-derived 68Ga. It ensures the removal of 68Ge …

Processing of generator-produced 68Ga for medical application

KP Zhernosekov, DV Filosofov, RP Baum… - Journal of Nuclear …, 2007 - Soc Nuclear Med
The 68Ge/68Ga generator provides an excellent source of positron-emitting 68Ga. However,
newly available “ionic” 68Ge/68Ga radionuclide generators are not necessarily optimized for …

[HTML][HTML] Validation of quality control parameters of cassette-based gallium-68-DOTA-Tyr3-octreotate synthesis

A Sammartano, S Migliari, M Scarlattei… - Indian Journal of …, 2020 - journals.lww.com
Materials and Methods: Preparation of Ga-68-DOTATATE was performed according to the
current European Union-good manufacturing practices, the current good radiopharmacy …