Objectives: In diabetes, extended adrenergic receptor stimulation with hyperglycemia and
insulin deficiency is associated with cardiac autonomic dysfunction. Clinically evident …

BACKGROUND: 123I-metaiodobenzylguanidine (MIBG) myocardial scintigraphy is a useful
tool for diagnosing cardiac autonomic neuropathy (CAN) in non–insulin-dependent diabetes …

Autonomic dysfunction is associated with increased mortality in diabetic patients. To
evaluate the cardiac autonomic dysfunction in these patients, a prospective study was …

To evaluate the presence and extent of global and regional distributions of cardiac
sympathetic dysinnervation in Type 2 diabetes mellitus I-123-metaiodobenzylguanidine (I …

Radio-labeled metaiodobenzylguanidine (MIBG) is considered an established sympa-thetic
neuron imaging agent capable of scintigraphically visualizing the organs richly innervated …

Abstract I-123 metaiodobenzylguanidine (MIBG) scintigraphy is a new method to evaluate
cardiac sympathetic nerve disturbance in patients with diabetes mellitus. Epalrestat …

Cardiovascular autonomic neuropathy (CAN) is a common complication of diabetes, which
results in disabling clinical manifestations and may predispose to sudden cardiac death …

Diabetic neuropathy is thought to comprise a reversible metabolic and an irreversible
structural component of neuronal abnormality. To investigate whether the cardiac …

The objectives of this clinical study using iodine-123 metaiodobenzylguanidine (MIBG)
scintigraphy were (a) to evaluate cardiac sympathetic denervation in non-insulin-dependent …

Background Although autonomic neuropathy is frequently recognized in patients with
diabetes mellitus, it is uncertain whether cardiac sympathetic neuropathy may play a role in …